MARDy: Mycology Antifungal Resistance Database

Anthony Nash, Thomas Sewell, Rhys A Farrer, Alireza Abdolrasouli, Jennifer M G Shelton, Matthew C Fisher, Johanna Rhodes

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Abstract

Summary: The increase of antifungal drug resistance is a major global human health concern and threatens agriculture and food security; in order to tackle these concerns, it is important to understand the mechanisms that cause antifungal resistance. The curated Mycology Antifungal Resistance Database (MARDy) is a web-service of antifungal drug resistance mechanisms, including amino acid substitutions, tandem repeat sequences and genome ploidy. MARDy is implemented on a Linux, Apache, MySQL and PHP web development platform and includes a local installation of BLASTn of the database of curated genes.

Availability and implementation: MARDy can be accessed at http://www.mardy.net and is free to use. The complete database can be retrieved, ordered by organism, gene and drug. Missing or new mycological antifungal resistance data can be relayed to the development team through a contribute entry form. Updates and news will be publicized via a dedicated Twitter feed: @MARDYfungi.

Original languageEnglish
Pages (from-to)3233-3234
Number of pages2
JournalBioinformatics
Volume34
Issue number18
Early online date20 Apr 2018
DOIs
Publication statusPublished - 15 Sep 2018

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    Nash, A., Sewell, T., Farrer, R. A., Abdolrasouli, A., Shelton, J. M. G., Fisher, M. C., & Rhodes, J. (2018). MARDy: Mycology Antifungal Resistance Database. Bioinformatics, 34(18), 3233-3234. https://doi.org/10.1093/bioinformatics/bty321