Marine metabolites and metal ion chelation

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Citations (Scopus)

Abstract

This chapter covers the unique ability of marine invertebrates to bioconcentrate transition metals by up to 8 orders of magnitude above background concentrations. A brief introduction deals with the bioinorganic principles of the subject matter and the natural concentrations of metals in the environment. Next, previous metal surveys of marine invertebrates and the potential reasons for hyperaccumulation are discussed, and this is followed by a section on previously isolated marine natural product-transition metal complexes. Studies on marine natural product complexation using physical methods are described in the context of their binding specificity and affinity. Many of these studies were conducted to try and discover potential functions for the marine natural product-transition metal complexes. Methodological aspects to discover new complexes of this type are discussed, especially hyphenated techniques utilizing elemental and molecular mass spectrometric methods. A final section proposes a rational way to uncover new marine natural product-transition metal complexes and potential methods to determine their function in nature.

Original languageEnglish
Title of host publicationHandbook of Marine Natural Products
PublisherSpringer Netherlands
Chapter16
Pages861-892
Number of pages32
Volume1
ISBN (Electronic)9789048138340
ISBN (Print)9789048138333
DOIs
Publication statusPublished - 8 Mar 2012

Fingerprint

Metabolites
Chelation
Biological Products
Transition metals
Metal ions
Coordination Complexes
Metals
Ions
Invertebrates
Molecular mass
Complexation

Keywords

  • metal complex
  • inductively coupled mass spectrometry
  • MARINE INVERTEBRATE
  • marine natural product
  • CALCAREOUS SPONGE

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Wright, S. H., Raab, A., Feldmann, J., Krupp, E., & Jaspars, M. (2012). Marine metabolites and metal ion chelation. In Handbook of Marine Natural Products (Vol. 1, pp. 861-892). Springer Netherlands. https://doi.org/10.1007/978-90-481-3834-0_16

Marine metabolites and metal ion chelation. / Wright, Stephen H.; Raab, Andrea; Feldmann, Jörg; Krupp, Eva; Jaspars, Marcel.

Handbook of Marine Natural Products. Vol. 1 Springer Netherlands, 2012. p. 861-892.

Research output: Chapter in Book/Report/Conference proceedingChapter

Wright, SH, Raab, A, Feldmann, J, Krupp, E & Jaspars, M 2012, Marine metabolites and metal ion chelation. in Handbook of Marine Natural Products. vol. 1, Springer Netherlands, pp. 861-892. https://doi.org/10.1007/978-90-481-3834-0_16
Wright SH, Raab A, Feldmann J, Krupp E, Jaspars M. Marine metabolites and metal ion chelation. In Handbook of Marine Natural Products. Vol. 1. Springer Netherlands. 2012. p. 861-892 https://doi.org/10.1007/978-90-481-3834-0_16
Wright, Stephen H. ; Raab, Andrea ; Feldmann, Jörg ; Krupp, Eva ; Jaspars, Marcel. / Marine metabolites and metal ion chelation. Handbook of Marine Natural Products. Vol. 1 Springer Netherlands, 2012. pp. 861-892
@inbook{e25834b0af2a41fa8441cc25034cebc5,
title = "Marine metabolites and metal ion chelation",
abstract = "This chapter covers the unique ability of marine invertebrates to bioconcentrate transition metals by up to 8 orders of magnitude above background concentrations. A brief introduction deals with the bioinorganic principles of the subject matter and the natural concentrations of metals in the environment. Next, previous metal surveys of marine invertebrates and the potential reasons for hyperaccumulation are discussed, and this is followed by a section on previously isolated marine natural product-transition metal complexes. Studies on marine natural product complexation using physical methods are described in the context of their binding specificity and affinity. Many of these studies were conducted to try and discover potential functions for the marine natural product-transition metal complexes. Methodological aspects to discover new complexes of this type are discussed, especially hyphenated techniques utilizing elemental and molecular mass spectrometric methods. A final section proposes a rational way to uncover new marine natural product-transition metal complexes and potential methods to determine their function in nature.",
keywords = "metal complex, inductively coupled mass spectrometry, MARINE INVERTEBRATE, marine natural product, CALCAREOUS SPONGE",
author = "Wright, {Stephen H.} and Andrea Raab and J{\"o}rg Feldmann and Eva Krupp and Marcel Jaspars",
year = "2012",
month = "3",
day = "8",
doi = "10.1007/978-90-481-3834-0_16",
language = "English",
isbn = "9789048138333",
volume = "1",
pages = "861--892",
booktitle = "Handbook of Marine Natural Products",
publisher = "Springer Netherlands",
address = "Netherlands",

}

TY - CHAP

T1 - Marine metabolites and metal ion chelation

AU - Wright, Stephen H.

AU - Raab, Andrea

AU - Feldmann, Jörg

AU - Krupp, Eva

AU - Jaspars, Marcel

PY - 2012/3/8

Y1 - 2012/3/8

N2 - This chapter covers the unique ability of marine invertebrates to bioconcentrate transition metals by up to 8 orders of magnitude above background concentrations. A brief introduction deals with the bioinorganic principles of the subject matter and the natural concentrations of metals in the environment. Next, previous metal surveys of marine invertebrates and the potential reasons for hyperaccumulation are discussed, and this is followed by a section on previously isolated marine natural product-transition metal complexes. Studies on marine natural product complexation using physical methods are described in the context of their binding specificity and affinity. Many of these studies were conducted to try and discover potential functions for the marine natural product-transition metal complexes. Methodological aspects to discover new complexes of this type are discussed, especially hyphenated techniques utilizing elemental and molecular mass spectrometric methods. A final section proposes a rational way to uncover new marine natural product-transition metal complexes and potential methods to determine their function in nature.

AB - This chapter covers the unique ability of marine invertebrates to bioconcentrate transition metals by up to 8 orders of magnitude above background concentrations. A brief introduction deals with the bioinorganic principles of the subject matter and the natural concentrations of metals in the environment. Next, previous metal surveys of marine invertebrates and the potential reasons for hyperaccumulation are discussed, and this is followed by a section on previously isolated marine natural product-transition metal complexes. Studies on marine natural product complexation using physical methods are described in the context of their binding specificity and affinity. Many of these studies were conducted to try and discover potential functions for the marine natural product-transition metal complexes. Methodological aspects to discover new complexes of this type are discussed, especially hyphenated techniques utilizing elemental and molecular mass spectrometric methods. A final section proposes a rational way to uncover new marine natural product-transition metal complexes and potential methods to determine their function in nature.

KW - metal complex

KW - inductively coupled mass spectrometry

KW - MARINE INVERTEBRATE

KW - marine natural product

KW - CALCAREOUS SPONGE

UR - http://www.scopus.com/inward/record.url?scp=85000687594&partnerID=8YFLogxK

U2 - 10.1007/978-90-481-3834-0_16

DO - 10.1007/978-90-481-3834-0_16

M3 - Chapter

SN - 9789048138333

VL - 1

SP - 861

EP - 892

BT - Handbook of Marine Natural Products

PB - Springer Netherlands

ER -