Materials and methods for medical imaging

Timothy Andrew Davies Smith; Laurent Alain Claude Trembleau; Abbie McLaughlin; Michael Simpson

Materials and methods for medical imaging

Timothy Andrew Davies Smith (Inventor), Laurent Alain Claude Trembleau (Inventor), Abbie McLaughlin (Inventor), Michael Simpson (Inventor)

Research output: Patent

Abstract

The invention provides labelled platform conjugates, comprising (i) a labelling platformn (such as a dendrimer or nanoparticle) and (ii) a target binding moiety, wherein the labelling platform has at least one positron emitter attached thereto. The conjugates can be used to flexibly label antibodies or the like, with the positron emitted being added as a simple final step to a positron emitter attachment site, which is a particular advantage when using short halt-life isotopes such as18F. The invention further provides processes and materials for use in preparing the conjugates, and methods of imaging employing them e.g. in Positron Emission Tomography (PET).

Original language	English
Patent number	GB2467494 (A)
IPC	WO2009056837
Publication status	Published - 2010

Cite this

@misc{83ddfda634034f3788c60d4e85140c03,

title = "Materials and methods for medical imaging",

abstract = "The invention provides labelled platform conjugates, comprising (i) a labelling platformn (such as a dendrimer or nanoparticle) and (ii) a target binding moiety, wherein the labelling platform has at least one positron emitter attached thereto. The conjugates can be used to flexibly label antibodies or the like, with the positron emitted being added as a simple final step to a positron emitter attachment site, which is a particular advantage when using short halt-life isotopes such as18F. The invention further provides processes and materials for use in preparing the conjugates, and methods of imaging employing them e.g. in Positron Emission Tomography (PET). ",

author = "Smith, {Timothy Andrew Davies} and Trembleau, {Laurent Alain Claude} and Abbie McLaughlin and Michael Simpson",

year = "2010",

language = "English",

type = "Patent",

note = "GB2467494 (A); WO2009056837",

}

TY - PAT

T1 - Materials and methods for medical imaging

AU - Smith, Timothy Andrew Davies

AU - Trembleau, Laurent Alain Claude

AU - McLaughlin, Abbie

AU - Simpson, Michael

PY - 2010

Y1 - 2010

N2 - The invention provides labelled platform conjugates, comprising (i) a labelling platformn (such as a dendrimer or nanoparticle) and (ii) a target binding moiety, wherein the labelling platform has at least one positron emitter attached thereto. The conjugates can be used to flexibly label antibodies or the like, with the positron emitted being added as a simple final step to a positron emitter attachment site, which is a particular advantage when using short halt-life isotopes such as18F. The invention further provides processes and materials for use in preparing the conjugates, and methods of imaging employing them e.g. in Positron Emission Tomography (PET).

AB - The invention provides labelled platform conjugates, comprising (i) a labelling platformn (such as a dendrimer or nanoparticle) and (ii) a target binding moiety, wherein the labelling platform has at least one positron emitter attached thereto. The conjugates can be used to flexibly label antibodies or the like, with the positron emitted being added as a simple final step to a positron emitter attachment site, which is a particular advantage when using short halt-life isotopes such as18F. The invention further provides processes and materials for use in preparing the conjugates, and methods of imaging employing them e.g. in Positron Emission Tomography (PET).

M3 - Patent

M1 - GB2467494 (A)

ER -

Materials and methods for medical imaging

Abstract

Fingerprint

Cite this