Abstract
Fresh ET has been the conventional strategy in IVF, but there is a growing opinion suggesting that its maternal and perinatal outcomes can be enhanced by a policy of elective freezing of embryos, followed by transfer at a later date. Available studies suggest a number of improved maternal and perinatal outcomes after frozen ET, although there is also a suggestion of large for gestational age babies associated with this strategy. The observational nature of the available data limit our confidence in the results of available studies. A genuinely unbiased estimate of the advantages of a policy of elective ET can only be confirmed by a definitive randomized controlled trial with an adequate length of follow-up of the offspring. (C)2016 by American Society for Reproductive Medicine.
| Original language | English |
|---|---|
| Pages (from-to) | 241-243 |
| Number of pages | 3 |
| Journal | Fertility and Sterility |
| Volume | 106 |
| Issue number | 2 |
| Early online date | 13 Jul 2016 |
| DOIs |
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| Publication status | Published - Aug 2016 |
Keywords
- frozen embryo transfer
- perinatal
- maternal
- outcomes
- assisted reproductive technology
- metaanalysis
- fertilization
- IVF
- protocol
- cycles
- born