Matrix metalloproteinase-1 promoter polymorphisms and changes in left ventricular volume following acute myocardial infarction

T. N. Martin, D. E. Penney, J. A. L. Smith, B. A. Groenning, H. J. Dargie, Graham Scott Hillis

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    Abstract

    The relation between matrix metalloproteinase-1 promoter genotype and remodeling was studied in 42 patients after their first acute myocardial infarctions. Patients possessing 2 GG alleles were at increased risk for remodeling compared with homozygotes for the G allele and heterozygotes possessing 1 G and 1 GG allele. (C) 2004 by Excerpta Medica, Inc.

    Original languageEnglish
    Pages (from-to)1044-1046
    Number of pages2
    JournalThe American Journal of Cardiology
    Volume94
    DOIs
    Publication statusPublished - 2004

    Keywords

    • SINGLE NUCLEOTIDE POLYMORPHISM
    • EXTRACELLULAR-MATRIX
    • CARDIAC DYSFUNCTION
    • HEART-FAILURE
    • SUSCEPTIBILITY
    • INVASIVENESS
    • PROGRESSION
    • DISRUPTION
    • EXPRESSION

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