Mechanisms of increased acid secretion after eradication of Helicobacter pylori infection

E M  El-Omar

doi:10.1136/gut.2005.071779

Mechanisms of increased acid secretion after eradication of Helicobacter pylori infection

E M El-Omar

Applied Medicine

Research output: Contribution to journal › Editorial

35 Citations (Scopus)

Abstract

Eradication of Helicobacter pylori infection leads to recovery of gastric acid secretion in some individuals but the mechanism is not fully understood. In the short term, there is an impressive increase in expression of H+/K+-ATPase pumps without an increase in the number of parietal cells. Longer follow up studies are needed to see if the parietal cell mass eventually recovers.

Original language	English
Pages (from-to)	144-146
Number of pages	3
Journal	Gut
Volume	55
DOIs	https://doi.org/10.1136/gut.2005.071779
Publication status	Published - 2006

Keywords

PARIETAL-CELLS
GASTRIC-ACID
INTERLEUKIN-1-BETA
CARCINOGENESIS
APOPTOSIS
CORPUS

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10.1136/gut.2005.071779

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title = "Mechanisms of increased acid secretion after eradication of Helicobacter pylori infection",

abstract = "Eradication of Helicobacter pylori infection leads to recovery of gastric acid secretion in some individuals but the mechanism is not fully understood. In the short term, there is an impressive increase in expression of H+/K+-ATPase pumps without an increase in the number of parietal cells. Longer follow up studies are needed to see if the parietal cell mass eventually recovers.",

keywords = "PARIETAL-CELLS, GASTRIC-ACID, INTERLEUKIN-1-BETA, CARCINOGENESIS, APOPTOSIS, CORPUS",

author = "El-Omar, {E M}",

year = "2006",

doi = "10.1136/gut.2005.071779",

language = "English",

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pages = "144--146",

journal = "Gut",

issn = "0017-5749",

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AU - El-Omar, E M

PY - 2006

Y1 - 2006

N2 - Eradication of Helicobacter pylori infection leads to recovery of gastric acid secretion in some individuals but the mechanism is not fully understood. In the short term, there is an impressive increase in expression of H+/K+-ATPase pumps without an increase in the number of parietal cells. Longer follow up studies are needed to see if the parietal cell mass eventually recovers.

AB - Eradication of Helicobacter pylori infection leads to recovery of gastric acid secretion in some individuals but the mechanism is not fully understood. In the short term, there is an impressive increase in expression of H+/K+-ATPase pumps without an increase in the number of parietal cells. Longer follow up studies are needed to see if the parietal cell mass eventually recovers.

KW - PARIETAL-CELLS

KW - GASTRIC-ACID

KW - INTERLEUKIN-1-BETA

KW - CARCINOGENESIS

KW - APOPTOSIS

KW - CORPUS

U2 - 10.1136/gut.2005.071779

DO - 10.1136/gut.2005.071779

M3 - Editorial

SN - 0017-5749

VL - 55

SP - 144

EP - 146

JO - Gut

JF - Gut

ER -

Mechanisms of increased acid secretion after eradication of Helicobacter pylori infection

Abstract

Keywords

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