Medial prefrontal activity predicts memory for self.

C Neil MacRae, J. M. Moran, T. F. Heatherton, J. F. Banfield, W. M. Kelley

Research output: Contribution to journalArticlepeer-review

423 Citations (Scopus)

Abstract

The ability to remember the past depends on cognitive operations that are recruited when information is initially encountered. In the current experiment, we investigated neural processes that subserve the memorability of a fundamental class of social information: self-knowledge. Participants evaluated the extent to which a series of personality characteristics were self-descriptive. Brain activation was measured using event-related functional magnetic resonance imaging (fMRI) and contrasted based on: (i) whether each word was later remembered or forgotten; and (ii) whether or not each item was judged to be self-relevant. Results revealed that activity in medial prefrontal cortex predicted both subsequent memory performance and judgements of self-relevance. These findings extend current understanding of the nature and functioning of human memory.

Original languageEnglish
Pages (from-to)647-654
Number of pages7
JournalCerebral Cortex
Volume14
DOIs
Publication statusPublished - 2004

Keywords

  • fMRI
  • memory
  • medial prefrontal cortex
  • social cognition
  • self
  • EVENT-RELATED FMRI
  • EPISODIC MEMORY
  • AMYGDALA ACTIVITY
  • FUNCTIONAL MRI
  • BRAIN ACTIVITY
  • DEFAULT MODE
  • CORTEX
  • RECALL
  • TASK
  • RETRIEVAL

Cite this