Medical abortion at 9-13 weeks' gestation: a review of 1076 consecutive cases

Haitham Hamoda, Premila Wencesiaus Ashok, G. M. M. Flett, Alexander Allan Templeton

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Objective: The aim of the study was to assess the use, efficacy and factors influencing the outcome of medical abortion at 9-13 weeks' gestation.

Methods: Retrospective chart review of consecutive women undergoing medical abortion at 9-13 weeks' gestation was done.

Results: A total of 1927 abortions were carried out at 9-13 weeks' gestation, of which 1076 (55.8%) were undertaken medically. Efficacy decreased with increasing gestation (p=.02). Surgical evacuation was carried out in 45 (4.2%) women including 10 (2.7%) at 64-70 days, 11 (3.3%) at 71-77 days, 10 (5.1%) at 78-84 days and 14 (8.0%) at 85-91 days of gestation (p=.02). Indications for surgery included continuing pregnancy [16 (1.5%) women], retained sac [5 (0.5%)], incomplete abortion [20 (1.9%)] and emergency curettage for bleeding [4 (0.4%)]. The number of misoprostol doses used and the induction-to-abortion interval both significantly increased with gestation (p<.001), while analgesia requirements did not vary with increasing gestation (p=.18).

Conclusions: Medical abortion at 9-13 weeks' gestation is an effective alternative to surgery. Medical methods should be offered routinely at these gestations, thus increasing women's choice. © 2005 Elsevier Inc. All rights reserved.

Original languageEnglish
Pages (from-to)327-332
Number of pages5
JournalContraception
Volume71
DOIs
Publication statusPublished - 2005

Keywords

  • late first trimester
  • medical abortion
  • mifepristone
  • misoprostol
  • SURGICAL VACUUM ASPIRATION
  • FOLLOW-UP VISITS
  • EXPECTANT MANAGEMENT
  • 1ST-TRIMESTER MISCARRIAGE
  • ENDOMETRIAL THICKNESS
  • MIFEPRISTONE
  • PREGNANCY
  • TRIMESTER
  • GEMEPROST
  • TERMINATION

Cite this

Medical abortion at 9-13 weeks' gestation: a review of 1076 consecutive cases. / Hamoda, Haitham; Ashok, Premila Wencesiaus; Flett, G. M. M.; Templeton, Alexander Allan.

In: Contraception, Vol. 71, 2005, p. 327-332.

Research output: Contribution to journalArticle

@article{270f3325cfa444699c7a509455b13a7f,
title = "Medical abortion at 9-13 weeks' gestation: a review of 1076 consecutive cases",
abstract = "Objective: The aim of the study was to assess the use, efficacy and factors influencing the outcome of medical abortion at 9-13 weeks' gestation.Methods: Retrospective chart review of consecutive women undergoing medical abortion at 9-13 weeks' gestation was done.Results: A total of 1927 abortions were carried out at 9-13 weeks' gestation, of which 1076 (55.8{\%}) were undertaken medically. Efficacy decreased with increasing gestation (p=.02). Surgical evacuation was carried out in 45 (4.2{\%}) women including 10 (2.7{\%}) at 64-70 days, 11 (3.3{\%}) at 71-77 days, 10 (5.1{\%}) at 78-84 days and 14 (8.0{\%}) at 85-91 days of gestation (p=.02). Indications for surgery included continuing pregnancy [16 (1.5{\%}) women], retained sac [5 (0.5{\%})], incomplete abortion [20 (1.9{\%})] and emergency curettage for bleeding [4 (0.4{\%})]. The number of misoprostol doses used and the induction-to-abortion interval both significantly increased with gestation (p<.001), while analgesia requirements did not vary with increasing gestation (p=.18).Conclusions: Medical abortion at 9-13 weeks' gestation is an effective alternative to surgery. Medical methods should be offered routinely at these gestations, thus increasing women's choice. © 2005 Elsevier Inc. All rights reserved.",
keywords = "late first trimester, medical abortion, mifepristone, misoprostol, SURGICAL VACUUM ASPIRATION, FOLLOW-UP VISITS, EXPECTANT MANAGEMENT, 1ST-TRIMESTER MISCARRIAGE, ENDOMETRIAL THICKNESS, MIFEPRISTONE, PREGNANCY, TRIMESTER, GEMEPROST, TERMINATION",
author = "Haitham Hamoda and Ashok, {Premila Wencesiaus} and Flett, {G. M. M.} and Templeton, {Alexander Allan}",
year = "2005",
doi = "10.1016/j.contraception.2004.10.015",
language = "English",
volume = "71",
pages = "327--332",
journal = "Contraception",
issn = "0010-7824",
publisher = "Elsevier USA",

}

TY - JOUR

T1 - Medical abortion at 9-13 weeks' gestation: a review of 1076 consecutive cases

AU - Hamoda, Haitham

AU - Ashok, Premila Wencesiaus

AU - Flett, G. M. M.

AU - Templeton, Alexander Allan

PY - 2005

Y1 - 2005

N2 - Objective: The aim of the study was to assess the use, efficacy and factors influencing the outcome of medical abortion at 9-13 weeks' gestation.Methods: Retrospective chart review of consecutive women undergoing medical abortion at 9-13 weeks' gestation was done.Results: A total of 1927 abortions were carried out at 9-13 weeks' gestation, of which 1076 (55.8%) were undertaken medically. Efficacy decreased with increasing gestation (p=.02). Surgical evacuation was carried out in 45 (4.2%) women including 10 (2.7%) at 64-70 days, 11 (3.3%) at 71-77 days, 10 (5.1%) at 78-84 days and 14 (8.0%) at 85-91 days of gestation (p=.02). Indications for surgery included continuing pregnancy [16 (1.5%) women], retained sac [5 (0.5%)], incomplete abortion [20 (1.9%)] and emergency curettage for bleeding [4 (0.4%)]. The number of misoprostol doses used and the induction-to-abortion interval both significantly increased with gestation (p<.001), while analgesia requirements did not vary with increasing gestation (p=.18).Conclusions: Medical abortion at 9-13 weeks' gestation is an effective alternative to surgery. Medical methods should be offered routinely at these gestations, thus increasing women's choice. © 2005 Elsevier Inc. All rights reserved.

AB - Objective: The aim of the study was to assess the use, efficacy and factors influencing the outcome of medical abortion at 9-13 weeks' gestation.Methods: Retrospective chart review of consecutive women undergoing medical abortion at 9-13 weeks' gestation was done.Results: A total of 1927 abortions were carried out at 9-13 weeks' gestation, of which 1076 (55.8%) were undertaken medically. Efficacy decreased with increasing gestation (p=.02). Surgical evacuation was carried out in 45 (4.2%) women including 10 (2.7%) at 64-70 days, 11 (3.3%) at 71-77 days, 10 (5.1%) at 78-84 days and 14 (8.0%) at 85-91 days of gestation (p=.02). Indications for surgery included continuing pregnancy [16 (1.5%) women], retained sac [5 (0.5%)], incomplete abortion [20 (1.9%)] and emergency curettage for bleeding [4 (0.4%)]. The number of misoprostol doses used and the induction-to-abortion interval both significantly increased with gestation (p<.001), while analgesia requirements did not vary with increasing gestation (p=.18).Conclusions: Medical abortion at 9-13 weeks' gestation is an effective alternative to surgery. Medical methods should be offered routinely at these gestations, thus increasing women's choice. © 2005 Elsevier Inc. All rights reserved.

KW - late first trimester

KW - medical abortion

KW - mifepristone

KW - misoprostol

KW - SURGICAL VACUUM ASPIRATION

KW - FOLLOW-UP VISITS

KW - EXPECTANT MANAGEMENT

KW - 1ST-TRIMESTER MISCARRIAGE

KW - ENDOMETRIAL THICKNESS

KW - MIFEPRISTONE

KW - PREGNANCY

KW - TRIMESTER

KW - GEMEPROST

KW - TERMINATION

U2 - 10.1016/j.contraception.2004.10.015

DO - 10.1016/j.contraception.2004.10.015

M3 - Article

VL - 71

SP - 327

EP - 332

JO - Contraception

JF - Contraception

SN - 0010-7824

ER -