Medical management of early fetal demise using sublingual misoprostol

Prabhath Thanuja Wagaarachchi; Premila Wencesiaus Ashok; Alexander Allan Templeton; Norman Smith

doi:10.1111/j.1471-0528.2002.01075.x

Medical management of early fetal demise using sublingual misoprostol

Prabhath Thanuja Wagaarachchi, Premila Wencesiaus Ashok, Alexander Allan Templeton, Norman Smith

Applied Health Sciences

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

The aim of this study was to determine the efficacy of mifepristone in combination with sublingual misoprostol for the medical management of early fetal demise. Fifty-six consecutive women were studied prospectively. The mean (SD) gestation at diagnosis was 9.6 weeks (1.84). Four women had complete miscarriage with mifepristone alone. The overall success rate was 83.9% and the median induction-miscarriage interval was 8.19 hours (range 0.83 to 37.50 hours). Of those women who had a successful outcome, 91.5% were satisfied with the regimen. Sublingual misoprostol in combination with mifepristone is an effective and safe altemative to vaginal or oral misoprostol in the management of early fetal demise.

Original language	English
Pages (from-to)	462-465
Number of pages	3
Journal	BJOG-An International Journal of Obstetrics and Gynaecology
Volume	109
Issue number	4
DOIs	https://doi.org/10.1111/j.1471-0528.2002.01075.x
Publication status	Published - 2002

Keywords

VAGINAL MISOPROSTOL
ABORTION
MIFEPRISTONE
MISCARRIAGE
PREGNANCY

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10.1111/j.1471-0528.2002.01075.x

Cite this

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title = "Medical management of early fetal demise using sublingual misoprostol",

abstract = "The aim of this study was to determine the efficacy of mifepristone in combination with sublingual misoprostol for the medical management of early fetal demise. Fifty-six consecutive women were studied prospectively. The mean (SD) gestation at diagnosis was 9.6 weeks (1.84). Four women had complete miscarriage with mifepristone alone. The overall success rate was 83.9% and the median induction-miscarriage interval was 8.19 hours (range 0.83 to 37.50 hours). Of those women who had a successful outcome, 91.5% were satisfied with the regimen. Sublingual misoprostol in combination with mifepristone is an effective and safe altemative to vaginal or oral misoprostol in the management of early fetal demise.",

keywords = "VAGINAL MISOPROSTOL, ABORTION, MIFEPRISTONE, MISCARRIAGE, PREGNANCY",

author = "Wagaarachchi, {Prabhath Thanuja} and Ashok, {Premila Wencesiaus} and Templeton, {Alexander Allan} and Norman Smith",

year = "2002",

doi = "10.1111/j.1471-0528.2002.01075.x",

language = "English",

volume = "109",

pages = "462--465",

journal = "BJOG-An International Journal of Obstetrics and Gynaecology",

issn = "1470-0328",

publisher = "John Wiley & Sons, Ltd (10.1111)",

number = "4",

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TY - JOUR

T1 - Medical management of early fetal demise using sublingual misoprostol

AU - Wagaarachchi, Prabhath Thanuja

AU - Ashok, Premila Wencesiaus

AU - Templeton, Alexander Allan

AU - Smith, Norman

PY - 2002

Y1 - 2002

N2 - The aim of this study was to determine the efficacy of mifepristone in combination with sublingual misoprostol for the medical management of early fetal demise. Fifty-six consecutive women were studied prospectively. The mean (SD) gestation at diagnosis was 9.6 weeks (1.84). Four women had complete miscarriage with mifepristone alone. The overall success rate was 83.9% and the median induction-miscarriage interval was 8.19 hours (range 0.83 to 37.50 hours). Of those women who had a successful outcome, 91.5% were satisfied with the regimen. Sublingual misoprostol in combination with mifepristone is an effective and safe altemative to vaginal or oral misoprostol in the management of early fetal demise.

AB - The aim of this study was to determine the efficacy of mifepristone in combination with sublingual misoprostol for the medical management of early fetal demise. Fifty-six consecutive women were studied prospectively. The mean (SD) gestation at diagnosis was 9.6 weeks (1.84). Four women had complete miscarriage with mifepristone alone. The overall success rate was 83.9% and the median induction-miscarriage interval was 8.19 hours (range 0.83 to 37.50 hours). Of those women who had a successful outcome, 91.5% were satisfied with the regimen. Sublingual misoprostol in combination with mifepristone is an effective and safe altemative to vaginal or oral misoprostol in the management of early fetal demise.

KW - VAGINAL MISOPROSTOL

KW - ABORTION

KW - MIFEPRISTONE

KW - MISCARRIAGE

KW - PREGNANCY

U2 - 10.1111/j.1471-0528.2002.01075.x

DO - 10.1111/j.1471-0528.2002.01075.x

M3 - Article

VL - 109

SP - 462

EP - 465

JO - BJOG-An International Journal of Obstetrics and Gynaecology

JF - BJOG-An International Journal of Obstetrics and Gynaecology

SN - 1470-0328

IS - 4

ER -

Medical management of early fetal demise using sublingual misoprostol

Abstract

Keywords

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