Medical management of early fetal demise using sublingual misoprostol

Prabhath Thanuja Wagaarachchi, Premila Wencesiaus Ashok, Alexander Allan Templeton, Norman Smith

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32 Citations (Scopus)

Abstract

The aim of this study was to determine the efficacy of mifepristone in combination with sublingual misoprostol for the medical management of early fetal demise. Fifty-six consecutive women were studied prospectively. The mean (SD) gestation at diagnosis was 9.6 weeks (1.84). Four women had complete miscarriage with mifepristone alone. The overall success rate was 83.9% and the median induction-miscarriage interval was 8.19 hours (range 0.83 to 37.50 hours). Of those women who had a successful outcome, 91.5% were satisfied with the regimen. Sublingual misoprostol in combination with mifepristone is an effective and safe altemative to vaginal or oral misoprostol in the management of early fetal demise.

Original languageEnglish
Pages (from-to)462-465
Number of pages3
JournalBJOG-An International Journal of Obstetrics and Gynaecology
Volume109
Issue number4
DOIs
Publication statusPublished - 2002

Keywords

  • VAGINAL MISOPROSTOL
  • ABORTION
  • MIFEPRISTONE
  • MISCARRIAGE
  • PREGNANCY

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