Metabolism of linoleic acid by human gut bacteria: different routes for biosynthesis of conjugated linoleic acid

Estelle Devillard, Freda M. McIntosh, Sylvia H. Duncan, R. John Wallace

Research output: Contribution to journalArticle

130 Citations (Scopus)

Abstract

A survey of 30 representative strains of human gram-positive intestinal bacteria indicated that Roseburia species were among the most active in metabolizing linoleic acid (cis-9,cis-12-18:2). Different Roseburia spp. formed either vaccenic acid (trans-11-18:1) or a 10-hydroxy-18:1; these compounds are precursors of the health-promoting conjugated linoleic acid cis-9,trans-11-18:2 in human tissues and the intestine, respectively.

Original languageEnglish
Pages (from-to)2566-2570
Number of pages5
JournalJournal of Bacteriology
Volume189
Issue number6
DOIs
Publication statusPublished - Mar 2007

Keywords

  • unsaturated fatty-acids
  • butyrate-producing bacteria
  • stearic-acid
  • lactobacillus-acidophilus
  • vaccenic acid
  • GEN-NOV
  • biohydregenation
  • butyrivibrio
  • clostridium
  • health

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