Methylantimony compound formation in the medium of Scopulariopsis brevicaulis cultures: (CD3)-C-13-L-methionine as a source of the methyl group

P Andrewes, W R Cullen, J Feldmann, I Koch, E Polishchuk

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23 Citations (Scopus)

Abstract

The filamentous fungus Scopulariopsis brevicaulis produces nonvolatile methylantimony compounds (found in the medium) when grown in antimony(III)-rich medium. To investigate the methyl source, (CD3)-C-13-labelled L-methionine was added to the growth medium. After one month sodium borohydride reduction of media samples produced dimethylstibine and trimethylstibine. The methylstibines were separated on a packed GC column and obtained as gaseous fractions. Analysis of the methylstibines, in the gaseous fractions, by CGC-MS (lion-trap) established (CD3)-C-13 incorporation in both the trimethyl-and dimethyl-antimony compounds. Copyright (C) 1999 John Wiley & Sons, Ltd.

Original languageEnglish
Pages (from-to)681-687
Number of pages7
JournalApplied Organometallic Chemistry
Volume13
Publication statusPublished - 1999

Keywords

  • Scopulariopsis brevicaulis
  • L-methionine
  • potassium antimony tartrate
  • biomethylation
  • biotransformation
  • S-adenosylmethionine
  • methylantimony species
  • CHROMATOGRAPHY MASS-SPECTROMETRY
  • APIOTRICHUM-HUMICOLA
  • ANTIMONY COMPOUNDS
  • BIOMETHYLATION
  • SPECIATION

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