Miniature Untethered EEG Recorder Improves Advanced Neuroscience Methodologies

Christopher Crispin-Bailey (Corresponding Author), Jim Austin, Bettina Platt (Corresponding Author), Anthony Moulds, Barry Crouch

Research output: Contribution to journalArticle

Abstract

Rodent electroencephalography (EEG) in preclinical research is frequently conducted in behaving animals. However, the difficulty inherent in identifying EEG epochs associated with a particular behavior or cue is a significant obstacle to more efficient analysis. In this paper we highlight a new solution, using infrared event stamping to accurately synchronize EEG, recorded from superficial sites above the hippocampus and prefrontal cortex, with video motion tracking data in a transgenic Alzheimer’s disease (AD) mouse model. Epochs capturing specific behaviors were automatically identified and extracted prior to further analysis. This was achieved by the novel design of a ultraminiature wearable EEG recorder, the NAT-1 device, and its insitu IR recording module. The device is described in detail, and its contribution to enabling new neuroscience is demonstrated.
Original languageEnglish
JournalIEEE Transactions on Biomedical Circuits and Systems
Early online date14 Aug 2019
DOIs
Publication statusE-pub ahead of print - 14 Aug 2019

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Electroencephalography
Stamping
Animals
Infrared radiation

Keywords

  • Experimental neuroscience
  • EEG recording
  • low-power sensors

Cite this

Miniature Untethered EEG Recorder Improves Advanced Neuroscience Methodologies. / Crispin-Bailey, Christopher (Corresponding Author); Austin, Jim; Platt, Bettina (Corresponding Author); Moulds, Anthony; Crouch, Barry.

In: IEEE Transactions on Biomedical Circuits and Systems, 14.08.2019.

Research output: Contribution to journalArticle

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