Rodent electroencephalography (EEG) in preclinical research is frequently conducted in behaving animals. However, the difficulty inherent in identifying EEG epochs associated with a particular behavior or cue is a significant obstacle to more efficient analysis. In this paper we highlight a new solution, using infrared event stamping to accurately synchronize EEG, recorded from superficial sites above the hippocampus and prefrontal cortex, with video motion tracking data in a transgenic Alzheimer’s disease (AD) mouse model. Epochs capturing specific behaviors were automatically identified and extracted prior to further analysis. This was achieved by the novel design of a ultraminiature wearable EEG recorder, the NAT-1 device, and its insitu IR recording module. The device is described in detail, and its contribution to enabling new neuroscience is demonstrated.
|Number of pages||11|
|Journal||IEEE Transactions on Biomedical Circuits and Systems|
|Early online date||14 Aug 2019|
|Publication status||Published - Oct 2019|
- Experimental neuroscience
- EEG recording
- low-power sensors