Molecular phylogenetic analysis of Candida tropicalis isolates by multi-locus sequence typing

Mette D. Jacobsen, Amanda D. Davidson, Shu-Ying Li, Duncan J. Shaw, Neil A. R. Gow, Frank C. Odds

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Multi-locus sequencing data for 242 different isolates of Candida tropicalis generated a dendrogram showing 235 strains assigned to a single large recently evolved group which contained several small clonal clusters. Haplotype analysis of a representative strain subset revealed a high level of recombination events in an otherwise clonal population. Pairs of isolates from single sources showed non-identity attributable to loss of heterozygosity in some genes in a manner similar to that established for C. albicans. (c) 2008 Elsevier Inc. All rights reserved.

Original languageEnglish
Pages (from-to)1040-1042
Number of pages3
JournalFungal Genetics and Biology
Volume45
Issue number6
Early online date25 Mar 2008
DOIs
Publication statusPublished - Jun 2008

Keywords

  • Candida tropicalis
  • MLST
  • phylogenetics
  • albicans
  • genotypes
  • Eburst

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