Emerging evidence suggests that the gut microbiota plays an important role in the development of many diseases including diabetes, cardiovascular disease, and cancer. There have been tremendous advances in characterizing the microbial diversity within the gastrointestinal tract, but very little is known about their function and role within the human host. It is becoming widely accepted that the metabolic products produced by the gut bacteria are a major factor influencing human health and disease. However, in most cases, the products of metabolism are uncharacterized. Mass spectroscopic-based methodologies provide a vital tool for the characterization of these gut metabolites, and this chapter explores the use of this technique to evaluate the microbial metabolome.
|Title of host publication||Foodomics|
|Subtitle of host publication||Advanced Mass Spectrometry in Modern Food Science and Nutrition|
|Publisher||John Wiley & Sons Ltd.|
|Number of pages||23|
|Publication status||Published - 4 Mar 2013|
- Gut health
- Microbial metabolites