Multimodality magnetic resonance systems for studying free radicals in vivo

S. J. McCallum; I. Nicholson; D. J. Lurie

doi:10.1088/0031-9155/43/7/006

Multimodality magnetic resonance systems for studying free radicals in vivo

S. J. McCallum^*, I. Nicholson, D. J. Lurie

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The multimodality approach to in vivo detection of free radicals combines the relative benefits of three free radical detection modalities: conventional RF CW-ESR, LODESR and PEDRI. We have built apparatus capable of combining these modalities to allow sequential PEDRI and CW-ESR, sequential LODESR and proton NMR imaging and simultaneous LODESR and CW-ESR. These systems offer superior performance in terms of both the scope and quality of information over single-modality free radical detection systems.

Original language	English
Pages (from-to)	1857-1861
Number of pages	5
Journal	Physics in Medicine and Biology
Volume	43
Issue number	7
DOIs	https://doi.org/10.1088/0031-9155/43/7/006
Publication status	Published - 1 Jan 1998

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title = "Multimodality magnetic resonance systems for studying free radicals in vivo",

abstract = "The multimodality approach to in vivo detection of free radicals combines the relative benefits of three free radical detection modalities: conventional RF CW-ESR, LODESR and PEDRI. We have built apparatus capable of combining these modalities to allow sequential PEDRI and CW-ESR, sequential LODESR and proton NMR imaging and simultaneous LODESR and CW-ESR. These systems offer superior performance in terms of both the scope and quality of information over single-modality free radical detection systems.",

author = "McCallum, {S. J.} and I. Nicholson and Lurie, {D. J.}",

note = "This work was supported by the Leverhulme Trust (which funded SJMcC). IN was funded by the Medical Research Council.",

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AU - Nicholson, I.

AU - Lurie, D. J.

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AB - The multimodality approach to in vivo detection of free radicals combines the relative benefits of three free radical detection modalities: conventional RF CW-ESR, LODESR and PEDRI. We have built apparatus capable of combining these modalities to allow sequential PEDRI and CW-ESR, sequential LODESR and proton NMR imaging and simultaneous LODESR and CW-ESR. These systems offer superior performance in terms of both the scope and quality of information over single-modality free radical detection systems.

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