Abstract
We investigate an experimentally feasible synthetic genetic network consisting of two phase repulsively
coupled repressilators, which evokes multiple coexisting stable attractors with different features. We perform a
bifurcation analysis to determine and classify the dynamical structure of the system. Moreover, some of the
dynamical regimes found, such as inhomogeneous steady states and inhomogeneous limit cycles can further be
associated with artificial cell differentiation. We also report and characterize the emergence of chaotic dynamics
resulting from the intercell coupling.
coupled repressilators, which evokes multiple coexisting stable attractors with different features. We perform a
bifurcation analysis to determine and classify the dynamical structure of the system. Moreover, some of the
dynamical regimes found, such as inhomogeneous steady states and inhomogeneous limit cycles can further be
associated with artificial cell differentiation. We also report and characterize the emergence of chaotic dynamics
resulting from the intercell coupling.
| Original language | English |
|---|---|
| Article number | 031904 |
| Number of pages | 8 |
| Journal | Physical Review. E, Statistical, Nonlinear and Soft Matter Physics |
| Volume | 78 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 5 Sept 2008 |