Needle-free jet versus conventional needle injection for local anesthesia in men undergoing surgical sperm retrieval

L. D. Khoa; T. N. Quang; P. D. Toan; N. M.T. Loc; N. T.N. Diem; V. Q. Dang; H. N.A. Vu; B. W. Mol; D. J. Handelsman

doi:10.1111/andr.12557

Needle-free jet versus conventional needle injection for local anesthesia in men undergoing surgical sperm retrieval

L. D. Khoa^*, T. N. Quang, P. D. Toan, N. M.T. Loc, N. T.N. Diem, V. Q. Dang, H. N.A. Vu, B. W. Mol, D. J. Handelsman

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Background: Surgical sperm retrieval, requiring local anesthetic injection, is the most frequent surgical procedure in male infertility. However, needle phobia is common and may contribute to negative experiences or refusal of procedures employing needle injection. Objectives: The aim of this study was to compare the acceptability, safety, and efficacy of needle-free jet anesthetic technique (MadaJet) with conventional needle injection for surgical sperm retrievals in patients with azoospermia. Materials and methods: This single-blind randomized controlled trial (RCT) was included of 59 participants who underwent surgical sperm retrievals. Patients were randomly assigned to the needle-free jet (n = 29) or needle injection (n = 30) groups prior to undergoing the surgery. The primary endpoint was the pain score. Results: Baseline characteristics were comparable between the two groups. The safety and adverse outcomes were also not statistically significant difference (p > 0.05). The pain score in patients using needle-free jet was significantly lower than that in patients using needle injection (p < 0.05). Patients in MadaJet group had a significantly lower discomfort score during (p < 0.001) and after (p = 0.01) injection than those in the needle injection group. However, there was no significant difference in the fear score (before, during, and after) of MadaJet and needle injection (p = 0.98, p = 0.74, and p = 0.94, respectively). The mean time to onset of anesthesia was much shorter in the MadaJet group as compared with needle injection (10 ± 4 vs. 157.5 ± 71 s, p < 0.001). However, the duration of anesthesia in patients using MadaJet was shorter compared with those using needle injection (44 ± 13 vs. 63 ± 26 min, p < 0.001). Conclusion: In conclusion, for local anesthesia in patients undergoing surgical sperm retrieval, MadaJet produces less pain and discomfort with quicker time to onset and offset of anesthesia compared with conventional needle injection.

Original language	English
Pages (from-to)	69-75
Number of pages	7
Journal	Andrology
Volume	7
Issue number	1
Early online date	8 Nov 2018
DOIs	https://doi.org/10.1111/andr.12557
Publication status	Published - 7 Feb 2019

Keywords

anesthetic technique
azoospermia
needle injection
needle-free jet
sperm retrieval

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/andr.12557

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@article{aaeb4ba3ed824cffae173c7697449a70,

title = "Needle-free jet versus conventional needle injection for local anesthesia in men undergoing surgical sperm retrieval",

abstract = "Background: Surgical sperm retrieval, requiring local anesthetic injection, is the most frequent surgical procedure in male infertility. However, needle phobia is common and may contribute to negative experiences or refusal of procedures employing needle injection. Objectives: The aim of this study was to compare the acceptability, safety, and efficacy of needle-free jet anesthetic technique (MadaJet) with conventional needle injection for surgical sperm retrievals in patients with azoospermia. Materials and methods: This single-blind randomized controlled trial (RCT) was included of 59 participants who underwent surgical sperm retrievals. Patients were randomly assigned to the needle-free jet (n = 29) or needle injection (n = 30) groups prior to undergoing the surgery. The primary endpoint was the pain score. Results: Baseline characteristics were comparable between the two groups. The safety and adverse outcomes were also not statistically significant difference (p > 0.05). The pain score in patients using needle-free jet was significantly lower than that in patients using needle injection (p < 0.05). Patients in MadaJet group had a significantly lower discomfort score during (p < 0.001) and after (p = 0.01) injection than those in the needle injection group. However, there was no significant difference in the fear score (before, during, and after) of MadaJet and needle injection (p = 0.98, p = 0.74, and p = 0.94, respectively). The mean time to onset of anesthesia was much shorter in the MadaJet group as compared with needle injection (10 ± 4 vs. 157.5 ± 71 s, p < 0.001). However, the duration of anesthesia in patients using MadaJet was shorter compared with those using needle injection (44 ± 13 vs. 63 ± 26 min, p < 0.001). Conclusion: In conclusion, for local anesthesia in patients undergoing surgical sperm retrieval, MadaJet produces less pain and discomfort with quicker time to onset and offset of anesthesia compared with conventional needle injection.",

keywords = "anesthetic technique, azoospermia, needle injection, needle-free jet, sperm retrieval",

author = "Khoa, {L. D.} and Quang, {T. N.} and Toan, {P. D.} and Loc, {N. M.T.} and Diem, {N. T.N.} and Dang, {V. Q.} and Vu, {H. N.A.} and Mol, {B. W.} and Handelsman, {D. J.}",

year = "2019",

month = feb,

day = "7",

doi = "10.1111/andr.12557",

language = "English",

volume = "7",

pages = "69--75",

journal = "Andrology",

issn = "2047-2919",

publisher = "American Society of Andrology Inc.",

number = "1",

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TY - JOUR

T1 - Needle-free jet versus conventional needle injection for local anesthesia in men undergoing surgical sperm retrieval

AU - Khoa, L. D.

AU - Quang, T. N.

AU - Toan, P. D.

AU - Loc, N. M.T.

AU - Diem, N. T.N.

AU - Dang, V. Q.

AU - Vu, H. N.A.

AU - Mol, B. W.

AU - Handelsman, D. J.

PY - 2019/2/7

Y1 - 2019/2/7

N2 - Background: Surgical sperm retrieval, requiring local anesthetic injection, is the most frequent surgical procedure in male infertility. However, needle phobia is common and may contribute to negative experiences or refusal of procedures employing needle injection. Objectives: The aim of this study was to compare the acceptability, safety, and efficacy of needle-free jet anesthetic technique (MadaJet) with conventional needle injection for surgical sperm retrievals in patients with azoospermia. Materials and methods: This single-blind randomized controlled trial (RCT) was included of 59 participants who underwent surgical sperm retrievals. Patients were randomly assigned to the needle-free jet (n = 29) or needle injection (n = 30) groups prior to undergoing the surgery. The primary endpoint was the pain score. Results: Baseline characteristics were comparable between the two groups. The safety and adverse outcomes were also not statistically significant difference (p > 0.05). The pain score in patients using needle-free jet was significantly lower than that in patients using needle injection (p < 0.05). Patients in MadaJet group had a significantly lower discomfort score during (p < 0.001) and after (p = 0.01) injection than those in the needle injection group. However, there was no significant difference in the fear score (before, during, and after) of MadaJet and needle injection (p = 0.98, p = 0.74, and p = 0.94, respectively). The mean time to onset of anesthesia was much shorter in the MadaJet group as compared with needle injection (10 ± 4 vs. 157.5 ± 71 s, p < 0.001). However, the duration of anesthesia in patients using MadaJet was shorter compared with those using needle injection (44 ± 13 vs. 63 ± 26 min, p < 0.001). Conclusion: In conclusion, for local anesthesia in patients undergoing surgical sperm retrieval, MadaJet produces less pain and discomfort with quicker time to onset and offset of anesthesia compared with conventional needle injection.

AB - Background: Surgical sperm retrieval, requiring local anesthetic injection, is the most frequent surgical procedure in male infertility. However, needle phobia is common and may contribute to negative experiences or refusal of procedures employing needle injection. Objectives: The aim of this study was to compare the acceptability, safety, and efficacy of needle-free jet anesthetic technique (MadaJet) with conventional needle injection for surgical sperm retrievals in patients with azoospermia. Materials and methods: This single-blind randomized controlled trial (RCT) was included of 59 participants who underwent surgical sperm retrievals. Patients were randomly assigned to the needle-free jet (n = 29) or needle injection (n = 30) groups prior to undergoing the surgery. The primary endpoint was the pain score. Results: Baseline characteristics were comparable between the two groups. The safety and adverse outcomes were also not statistically significant difference (p > 0.05). The pain score in patients using needle-free jet was significantly lower than that in patients using needle injection (p < 0.05). Patients in MadaJet group had a significantly lower discomfort score during (p < 0.001) and after (p = 0.01) injection than those in the needle injection group. However, there was no significant difference in the fear score (before, during, and after) of MadaJet and needle injection (p = 0.98, p = 0.74, and p = 0.94, respectively). The mean time to onset of anesthesia was much shorter in the MadaJet group as compared with needle injection (10 ± 4 vs. 157.5 ± 71 s, p < 0.001). However, the duration of anesthesia in patients using MadaJet was shorter compared with those using needle injection (44 ± 13 vs. 63 ± 26 min, p < 0.001). Conclusion: In conclusion, for local anesthesia in patients undergoing surgical sperm retrieval, MadaJet produces less pain and discomfort with quicker time to onset and offset of anesthesia compared with conventional needle injection.

KW - anesthetic technique

KW - azoospermia

KW - needle injection

KW - needle-free jet

KW - sperm retrieval

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U2 - 10.1111/andr.12557

DO - 10.1111/andr.12557

M3 - Article

C2 - 30407744

AN - SCOPUS:85056201703

SN - 2047-2919

VL - 7

SP - 69

EP - 75

JO - Andrology

JF - Andrology

IS - 1

ER -

Needle-free jet versus conventional needle injection for local anesthesia in men undergoing surgical sperm retrieval

Abstract

Keywords

UN SDGs

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