Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy

A Hammers, M J Koepp, C Labbé, D J Brooks, M Thom, V J Cunningham, Jackie Duncan

Research output: Contribution to journalArticle

94 Citations (Scopus)

Abstract

To characterize abnormalities in neocortical central benzodiazepine receptor (cBZR) binding in patients with mesial temporal lobe epilepsy (mTLE) with unilateral hippocampal sclerosis (HS) using [(11)C]-flumazenil-(FMZ) PET and complementary voxel-based and quantitative volume-of-interest (VOI) methods.
Original languageEnglish
Pages (from-to)897-906
Number of pages10
JournalNeurology
Volume56
Issue number7
Publication statusPublished - 2001

    Fingerprint

Keywords

  • Adult
  • Carbon Radioisotopes
  • Epilepsy, Temporal Lobe
  • Female
  • Flumazenil
  • Humans
  • Male
  • Middle Aged
  • Neocortex
  • Tomography, Emission-Computed

Cite this

Hammers, A., Koepp, M. J., Labbé, C., Brooks, D. J., Thom, M., Cunningham, V. J., & Duncan, J. (2001). Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy. Neurology, 56(7), 897-906.