Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy

A Hammers, M J Koepp, C Labbé, D J Brooks, M Thom, V J Cunningham, Jackie Duncan

Research output: Contribution to journalArticlepeer-review

94 Citations (Scopus)

Abstract

To characterize abnormalities in neocortical central benzodiazepine receptor (cBZR) binding in patients with mesial temporal lobe epilepsy (mTLE) with unilateral hippocampal sclerosis (HS) using [(11)C]-flumazenil-(FMZ) PET and complementary voxel-based and quantitative volume-of-interest (VOI) methods.
Original languageEnglish
Pages (from-to)897-906
Number of pages10
JournalNeurology
Volume56
Issue number7
Publication statusPublished - 2001

Keywords

  • Adult
  • Carbon Radioisotopes
  • Epilepsy, Temporal Lobe
  • Female
  • Flumazenil
  • Humans
  • Male
  • Middle Aged
  • Neocortex
  • Tomography, Emission-Computed

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