Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy

A Hammers; M J Koepp; C Labbé; D J Brooks; M Thom; V J Cunningham; Jackie Duncan

Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy

A Hammers, M J Koepp, C Labbé, D J Brooks, M Thom, V J Cunningham, Jackie Duncan

Research output: Contribution to journal › Article › peer-review

Abstract

To characterize abnormalities in neocortical central benzodiazepine receptor (cBZR) binding in patients with mesial temporal lobe epilepsy (mTLE) with unilateral hippocampal sclerosis (HS) using [(11)C]-flumazenil-(FMZ) PET and complementary voxel-based and quantitative volume-of-interest (VOI) methods.

Original language	English
Pages (from-to)	897-906
Number of pages	10
Journal	Neurology
Volume	56
Issue number	7
Publication status	Published - 2001

Keywords

Adult
Carbon Radioisotopes
Epilepsy, Temporal Lobe
Female
Flumazenil
Humans
Male
Middle Aged
Neocortex
Tomography, Emission-Computed

Cite this

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title = "Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy",

abstract = "To characterize abnormalities in neocortical central benzodiazepine receptor (cBZR) binding in patients with mesial temporal lobe epilepsy (mTLE) with unilateral hippocampal sclerosis (HS) using [(11)C]-flumazenil-(FMZ) PET and complementary voxel-based and quantitative volume-of-interest (VOI) methods.",

keywords = "Adult, Carbon Radioisotopes, Epilepsy, Temporal Lobe, Female, Flumazenil, Humans, Male, Middle Aged, Neocortex, Tomography, Emission-Computed",

author = "A Hammers and Koepp, {M J} and C Labb{\'e} and Brooks, {D J} and M Thom and Cunningham, {V J} and Jackie Duncan",

year = "2001",

language = "English",

volume = "56",

pages = "897--906",

journal = "Neurology",

issn = "0028-3878",

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number = "7",

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TY - JOUR

T1 - Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy

AU - Hammers, A

AU - Koepp, M J

AU - Labbé, C

AU - Brooks, D J

AU - Thom, M

AU - Cunningham, V J

AU - Duncan, Jackie

PY - 2001

Y1 - 2001

N2 - To characterize abnormalities in neocortical central benzodiazepine receptor (cBZR) binding in patients with mesial temporal lobe epilepsy (mTLE) with unilateral hippocampal sclerosis (HS) using [(11)C]-flumazenil-(FMZ) PET and complementary voxel-based and quantitative volume-of-interest (VOI) methods.

AB - To characterize abnormalities in neocortical central benzodiazepine receptor (cBZR) binding in patients with mesial temporal lobe epilepsy (mTLE) with unilateral hippocampal sclerosis (HS) using [(11)C]-flumazenil-(FMZ) PET and complementary voxel-based and quantitative volume-of-interest (VOI) methods.

KW - Adult

KW - Carbon Radioisotopes

KW - Epilepsy, Temporal Lobe

KW - Female

KW - Flumazenil

KW - Humans

KW - Male

KW - Middle Aged

KW - Neocortex

KW - Tomography, Emission-Computed

M3 - Article

C2 - 11294927

SN - 0028-3878

VL - 56

SP - 897

EP - 906

JO - Neurology

JF - Neurology

IS - 7

ER -

Neocortical abnormalities of [11C]-flumazenil PET in mesial temporal lobe epilepsy

Abstract

Keywords

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