Neural signatures of stimulus features in visual working memory

a spatiotemporal approach

Helen M Morgan, Margaret C Jackson, Christoph Klein, Harald Mohr, Kimron L Shapiro, David E J Linden

Research output: Contribution to journalArticle

9 Citations (Scopus)
5 Downloads (Pure)

Abstract

We examined the neural signatures of stimulus features in visual working memory (WM) by integrating functional magnetic resonance imaging (fMRI) and event-related potential data recorded during mental manipulation of colors, rotation angles, and color-angle conjunctions. The N200, negative slow wave, and P3b were modulated by the information content of WM, and an fMRI-constrained source model revealed a progression in neural activity from posterior visual areas to higher order areas in the ventral and dorsal processing streams. Color processing was associated with activity in inferior frontal gyrus during encoding and retrieval, whereas angle processing involved right parietal regions during the delay interval. WM for color-angle conjunctions did not involve any additional neural processes. The finding that different patterns of brain activity underlie WM for color and spatial information is consistent with ideas that the ventral/dorsal "what/where" segregation of perceptual processing influences WM organization. The absence of characteristic signatures of conjunction-related brain activity, which was generally intermediate between the 2 single conditions, suggests that conjunction judgments are based on the coordinated activity of these 2 streams.
Original languageEnglish
Pages (from-to)187-197
Number of pages11
JournalCerebral Cortex
Volume20
Issue number1
Early online date8 May 2009
DOIs
Publication statusPublished - Jan 2010

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Short-Term Memory
Color
Magnetic Resonance Imaging
Parietal Lobe
Brain
Prefrontal Cortex
Evoked Potentials

Keywords

  • EEG
  • fMRI
  • source analysis
  • visual
  • working memory

Cite this

Neural signatures of stimulus features in visual working memory : a spatiotemporal approach. / Morgan, Helen M; Jackson, Margaret C; Klein, Christoph; Mohr, Harald; Shapiro, Kimron L; Linden, David E J.

In: Cerebral Cortex, Vol. 20, No. 1, 01.2010, p. 187-197.

Research output: Contribution to journalArticle

Morgan, Helen M ; Jackson, Margaret C ; Klein, Christoph ; Mohr, Harald ; Shapiro, Kimron L ; Linden, David E J. / Neural signatures of stimulus features in visual working memory : a spatiotemporal approach. In: Cerebral Cortex. 2010 ; Vol. 20, No. 1. pp. 187-197.
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