Neutralisation of SARS-CoV-2 by anatomical embalming solutions

Fabio Quondamatteo, Dora Corzo Leon, Cecilia Brassett, Ian J. Colquhoun, David C Davies, Peter Dockery, Grenham Sue, Simon Guild, Amanda Hunter, James Jones, Chris Tracey, Tracey Wilkinson, Carol Munro, Thomas H. Gillingwater, Simon Parson* (Corresponding Author)

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Teaching and learning anatomy by using human cadaveric specimens has been a foundation of medical and biomedical teaching for hundreds of years. Therefore, the majority of institutions that teach topographical anatomy rely on body donation programmes to provide specimens for both undergraduate and postgraduate teaching of gross anatomy. The COVID-19 pandemic has posed an unprecedented challenge to anatomy teaching because of the suspension of donor acceptance at most institutions. This was largely due to concerns about the potential transmissibility of the SARS-CoV-2 virus and the absence of data about the ability of embalming solutions to neutralise the virus. Twenty embalming solutions commonly used in institutions in the United Kingdom and Ireland were tested for their ability to neutralise SARS-CoV-2, using an established cytotoxicity assay. All embalming solutions tested neutralised SARS-CoV-2, with the majority of solutions being effective at high-working dilutions. These results suggest that successful embalming with the tested solutions can neutralise the SARS-CoV-2 virus, thereby facilitating the safe resumption of body donation programmes and cadaveric anatomy teaching.
Original languageEnglish
Pages (from-to)1221-1225
Number of pages5
JournalJournal of Anatomy
Volume239
Issue number5
Early online date11 Oct 2021
DOIs
Publication statusPublished - Nov 2021

Keywords

  • body donation
  • cadaver
  • fixation
  • preservation

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