Neutropenic acute acalculous cholecystitis (AAC) in a 12-year-old boy with T-acute lymphoblastic leukemia successfully managed with conservative treatment

Aldo Naselli (Corresponding Author), Hugh Bishop, Shonagh Walker, Adilia Warris

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Abstract

Acute acalculous cholecystitis (AAC) is an inflammation of the gallbladder without the presence of gallstones. In children with malignancies or chemotherapy-induced neutropenia, AAC is very rare. Clinical diagnosis of AAC remains difficult in this patient population but an early recognition followed by an appropriate intervention may confer a benefit. Only three pediatric patients with underlying hematological malignancies whose clinical treatment course was complicated by the development of AAC have been described. We describe a neutropenic pediatric patient who developed AAC following chemotherapy for acute T-cell acute lymphoblastic leukemia (T-ALL), which was successfully managed with conservative treatment.
Original languageEnglish
Pages (from-to)24-28
Number of pages5
JournalPediatric Hematology and Oncology
Volume34
Issue number1
Early online date13 Jan 2017
DOIs
Publication statusPublished - 2017

Keywords

  • AAC
  • conservative management
  • neutropenic fever
  • T-LLA

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