Nicorandil associated anal ulceration

Angus Watson; O. Al-Ozairi; Alison Fraser; M. Loudon; T. J. O'Kelly

doi:10.1016/S0140-6736(02)09710-6

Nicorandil associated anal ulceration

Angus Watson, O. Al-Ozairi, Alison Fraser, M. Loudon, T. J. O'Kelly

Applied Health Sciences

Research output: Contribution to journal › Article › peer-review

89 Citations (Scopus)

Abstract

Nicorandil is a vasodilator used to control angina. It has been associated with oral ulceration and stomatitis that resolves upon withdrawal of the drug. We report a series of five patients with non-specific anal ulceration, all of whom received nicorandil for symptomatic control of ischaemic heart disease. Histological appearances were similar and the ulcers healed on withdrawal of the drug. Our results suggest that nicorandil might be a cause of anal ulceration.

Original language	English
Pages (from-to)	546-547
Number of pages	1
Journal	The Lancet
Volume	360
Issue number	9332
DOIs	https://doi.org/10.1016/S0140-6736(02)09710-6
Publication status	Published - 17 Aug 2002

Keywords

MAJOR APHTHOUS ULCERS

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10.1016/S0140-6736(02)09710-6

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title = "Nicorandil associated anal ulceration",

abstract = "Nicorandil is a vasodilator used to control angina. It has been associated with oral ulceration and stomatitis that resolves upon withdrawal of the drug. We report a series of five patients with non-specific anal ulceration, all of whom received nicorandil for symptomatic control of ischaemic heart disease. Histological appearances were similar and the ulcers healed on withdrawal of the drug. Our results suggest that nicorandil might be a cause of anal ulceration.",

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T1 - Nicorandil associated anal ulceration

AU - Watson, Angus

AU - Al-Ozairi, O.

AU - Fraser, Alison

AU - Loudon, M.

AU - O'Kelly, T. J.

PY - 2002/8/17

Y1 - 2002/8/17

N2 - Nicorandil is a vasodilator used to control angina. It has been associated with oral ulceration and stomatitis that resolves upon withdrawal of the drug. We report a series of five patients with non-specific anal ulceration, all of whom received nicorandil for symptomatic control of ischaemic heart disease. Histological appearances were similar and the ulcers healed on withdrawal of the drug. Our results suggest that nicorandil might be a cause of anal ulceration.

AB - Nicorandil is a vasodilator used to control angina. It has been associated with oral ulceration and stomatitis that resolves upon withdrawal of the drug. We report a series of five patients with non-specific anal ulceration, all of whom received nicorandil for symptomatic control of ischaemic heart disease. Histological appearances were similar and the ulcers healed on withdrawal of the drug. Our results suggest that nicorandil might be a cause of anal ulceration.

KW - MAJOR APHTHOUS ULCERS

U2 - 10.1016/S0140-6736(02)09710-6

DO - 10.1016/S0140-6736(02)09710-6

M3 - Article

SN - 0140-6736

VL - 360

SP - 546

EP - 547

JO - The Lancet

JF - The Lancet

IS - 9332

ER -

Nicorandil associated anal ulceration

Abstract

Keywords

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