Oats and bowel disease

a systematic literature review

Frank Thies, Lindsey F. Masson, Paolo Boffetta, Penny Kris-Etherton

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Whole-grain foods such as oats may protect against colorectal cancer and have benefits on inflammatory bowel disease and coeliac disease. The present study aimed to systematically review the literature describing intervention studies that investigated the effects of oats or oat bran on risk factors for bowel disease. A literature search was conducted using Embase, Medline and the Cochrane library, which identified 654 potential articles. Thirty-eight articles describing twenty-nine studies met the inclusion criteria. Two studies carried out in participants with a history of colorectal adenomas found no effects of increased oat-bran intake on indirect risk makers for colorectal cancer. One of two interventions with oat bran in patients with ulcerative colitis showed small improvements in the patients' conditions. Most of the eleven studies carried out in adults with coeliac disease showed no negative effects of uncontaminated oat consumption. The fourteen studies carried out in volunteers with no history of bowel disease suggest that oats or oat bran can significantly increase stool weight and decrease constipation, but there is a lack of evidence to support a specific effect of oats on bowel function compared with other cereals. A long-term dietary intake of oats or oat bran could benefit inflammatory bowel disorders, but this remains to be proven. A protective effect on colorectal adenoma and cancer incidence has not yet been convincingly shown. The majority of patients with coeliac disease could consume up to 100 g/d of uncontaminated oats, which would increase the acceptability of, and adherence to, a gluten-free diet.
Original languageEnglish
Pages (from-to)S31-43
Number of pages13
JournalBritish Journal of Nutrition
Volume112
Issue numberS2
Early online date30 Sep 2014
DOIs
Publication statusPublished - Oct 2014

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Celiac Disease
Colorectal Neoplasms
Adenoma
Avena
Gluten-Free Diet
Constipation
Ulcerative Colitis
Inflammatory Bowel Diseases
Libraries
Volunteers
Weights and Measures
Food
Incidence

Keywords

  • oats
  • bowel disease
  • inflammatory bowel disease
  • coeliac disease
  • bowel cancer

Cite this

Oats and bowel disease : a systematic literature review. / Thies, Frank; Masson, Lindsey F.; Boffetta, Paolo; Kris-Etherton, Penny.

In: British Journal of Nutrition, Vol. 112, No. S2, 10.2014, p. S31-43.

Research output: Contribution to journalArticle

Thies, Frank ; Masson, Lindsey F. ; Boffetta, Paolo ; Kris-Etherton, Penny. / Oats and bowel disease : a systematic literature review. In: British Journal of Nutrition. 2014 ; Vol. 112, No. S2. pp. S31-43.
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abstract = "Whole-grain foods such as oats may protect against colorectal cancer and have benefits on inflammatory bowel disease and coeliac disease. The present study aimed to systematically review the literature describing intervention studies that investigated the effects of oats or oat bran on risk factors for bowel disease. A literature search was conducted using Embase, Medline and the Cochrane library, which identified 654 potential articles. Thirty-eight articles describing twenty-nine studies met the inclusion criteria. Two studies carried out in participants with a history of colorectal adenomas found no effects of increased oat-bran intake on indirect risk makers for colorectal cancer. One of two interventions with oat bran in patients with ulcerative colitis showed small improvements in the patients' conditions. Most of the eleven studies carried out in adults with coeliac disease showed no negative effects of uncontaminated oat consumption. The fourteen studies carried out in volunteers with no history of bowel disease suggest that oats or oat bran can significantly increase stool weight and decrease constipation, but there is a lack of evidence to support a specific effect of oats on bowel function compared with other cereals. A long-term dietary intake of oats or oat bran could benefit inflammatory bowel disorders, but this remains to be proven. A protective effect on colorectal adenoma and cancer incidence has not yet been convincingly shown. The majority of patients with coeliac disease could consume up to 100 g/d of uncontaminated oats, which would increase the acceptability of, and adherence to, a gluten-free diet.",
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