Obesity and fertility

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The prevalence of overweight and obesity in women of reproductive age has increased over the past 30 years. Infertility affects 1 in 7 couples, and female obesity is associated with anovulation. The mechanisms by which excessive fat delays time to pregnancy (TTP) appear rooted in ovulatory problems and direct effects on oocytes, causing poorer embryo development, as well as in effects on the endometrium. Weight loss in women has been shown to improve conception, but not necessarily live birth rates following fertility treatment, and further research in this area is needed. The obesity epidemic has been accompanied by a potential rise in male infertility, which has been attributed to hormonal disturbances and compromised semen parameters.

Original languageEnglish
Pages (from-to)5-10
Number of pages6
JournalHormone molecular biology and clinical investigation
Volume24
Issue number1
Early online date18 Aug 2015
DOIs
Publication statusPublished - 1 Oct 2015

Fingerprint

Fertility
Obesity
Time-to-Pregnancy
Anovulation
Birth Rate
Male Infertility
Live Birth
Endometrium
Semen
Infertility
Oocytes
Embryonic Development
Weight Loss
Fats
Research
Therapeutics

Keywords

  • body mass index (BMI)
  • fecundity
  • fertility
  • obesity
  • overweight

Cite this

Obesity and fertility. / Best, Damian; Bhattacharya, Siladitya.

In: Hormone molecular biology and clinical investigation, Vol. 24, No. 1, 01.10.2015, p. 5-10.

Research output: Contribution to journalArticle

@article{303e42bbec7047d5b81ca5511765fb83,
title = "Obesity and fertility",
abstract = "The prevalence of overweight and obesity in women of reproductive age has increased over the past 30 years. Infertility affects 1 in 7 couples, and female obesity is associated with anovulation. The mechanisms by which excessive fat delays time to pregnancy (TTP) appear rooted in ovulatory problems and direct effects on oocytes, causing poorer embryo development, as well as in effects on the endometrium. Weight loss in women has been shown to improve conception, but not necessarily live birth rates following fertility treatment, and further research in this area is needed. The obesity epidemic has been accompanied by a potential rise in male infertility, which has been attributed to hormonal disturbances and compromised semen parameters.",
keywords = "body mass index (BMI), fecundity, fertility, obesity, overweight",
author = "Damian Best and Siladitya Bhattacharya",
year = "2015",
month = "10",
day = "1",
doi = "10.1515/hmbci-2015-0023",
language = "English",
volume = "24",
pages = "5--10",
journal = "Hormone molecular biology and clinical investigation",
issn = "1868-1883",
publisher = "Walter de Gruyter GmbH",
number = "1",

}

TY - JOUR

T1 - Obesity and fertility

AU - Best, Damian

AU - Bhattacharya, Siladitya

PY - 2015/10/1

Y1 - 2015/10/1

N2 - The prevalence of overweight and obesity in women of reproductive age has increased over the past 30 years. Infertility affects 1 in 7 couples, and female obesity is associated with anovulation. The mechanisms by which excessive fat delays time to pregnancy (TTP) appear rooted in ovulatory problems and direct effects on oocytes, causing poorer embryo development, as well as in effects on the endometrium. Weight loss in women has been shown to improve conception, but not necessarily live birth rates following fertility treatment, and further research in this area is needed. The obesity epidemic has been accompanied by a potential rise in male infertility, which has been attributed to hormonal disturbances and compromised semen parameters.

AB - The prevalence of overweight and obesity in women of reproductive age has increased over the past 30 years. Infertility affects 1 in 7 couples, and female obesity is associated with anovulation. The mechanisms by which excessive fat delays time to pregnancy (TTP) appear rooted in ovulatory problems and direct effects on oocytes, causing poorer embryo development, as well as in effects on the endometrium. Weight loss in women has been shown to improve conception, but not necessarily live birth rates following fertility treatment, and further research in this area is needed. The obesity epidemic has been accompanied by a potential rise in male infertility, which has been attributed to hormonal disturbances and compromised semen parameters.

KW - body mass index (BMI)

KW - fecundity

KW - fertility

KW - obesity

KW - overweight

U2 - 10.1515/hmbci-2015-0023

DO - 10.1515/hmbci-2015-0023

M3 - Article

VL - 24

SP - 5

EP - 10

JO - Hormone molecular biology and clinical investigation

JF - Hormone molecular biology and clinical investigation

SN - 1868-1883

IS - 1

ER -