Osteoblast response to single wall carbon nanotube-PLLA composites

B. Annaz*, B. Reid, B. Olalde, M. J. Jurado, J. I. Alava, C. D. McCaig, I. R. Gibson

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This study showed that incorporation of single-walled carbon nanotubes (1wt%) in to PLLA polymer resulted in a large decrease in resistivity, but did not appear to affect the growth and viability of osteoblast-like cells. Also, incorporation of SWCNTs resulted in no significant difference in alkaline phosphatase activity, an important early-stage marker of osteogenic differentiation, of BMSC. These initial studies suggest that SWCNTs did not have a negative effect on cell behaviour, compared to results reported for MWCNT [2]; this could be related to the purity of CNTs used in the present study. Further, long term studies are required to determine if there is a toxic response to the SWCNTs as the PLLA degrades.

Original languageEnglish
Title of host publication8th World Biomaterials Congress 2008
Number of pages1
Volume2
Publication statusPublished - 1 Dec 2008
Event8th World Biomaterials Congress 2008, WBC 2008 - Amsterdam, Netherlands
Duration: 28 May 20081 Jun 2008

Conference

Conference8th World Biomaterials Congress 2008, WBC 2008
CountryNetherlands
CityAmsterdam
Period28/05/081/06/08

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