Over-the-counter (OTC) short-acting β2-agonist (SABA) purchase and asthma outcomes in SABINA III

H Farouk, W J Mattarucco, R M Barriga, H Wang, D Diaz, A Khattab, M P Gallego, A A Zaabi, D Price

Research output: Contribution to journalAbstractpeer-review

Abstract

Background: SABINA III showed that 18% of patients with asthma across 24 countries purchased SABA OTC;1 however, the clinical burden of such unregulated access to SABA is not known.Objective: To evaluate the clinical characteristics and outcomes of patients with asthma who purchase SABA OTC.Methods: This post-hoc analysis of SABINA III included patients with asthma aged ≥12 years with SABA prescriptions and/or self-reported OTC SABA purchase (canisters/year).Results: Of the 8351 patients in SABINA III, 318 had only OTC SABA, 3732 had only SABA prescriptions, and 1101, both prescriptions+OTC SABA (Table 1A). A higher proportion of patients with only OTC SABA vs the other groups were treated in primary care (36.2% vs 19.2% and 14.2%) and had no healthcare reimbursement (47.8% vs 23.8% and 35.5%). Of the 2927 patients prescribed ≥3 SABA canisters, 443 (15.1%) also had ≥3 OTC SABA. These 15.1% had a mean of 2.5 severe exacerbations in the previous year; 78.3% of them had ≥1 severe exacerbation and 65.2% had uncontrolled asthma (Table 1B).Conclusion: A subset of patients with ≥3 SABA canister prescriptions also purchased ≥3 SABA canisters OTC. These patients had a relatively high disease burden, emphasising the need for regular asthma reviews, for pharmacists to play a key role in monitoring SABA purchase, as well as policy changes to regulate SABA purchase and ensure access to affordable asthma care.FootnotesCite this article as Eur Respir J 2022; 60: Suppl. 66, 3434.This article was presented at the 2022 ERS International Congress, in session “-”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
Original languageEnglish
JournalEur Respir J
Volume60
Issue numberSuppl. 66
DOIs
Publication statusPublished - 4 Sep 2022
EventEuropean Respiratory Society (ERS) International Congress. - FIRA Barcelona Gran Via Congress Centre, Barcelona, Spain
Duration: 4 Sep 20226 Sep 2022
https://www.ersnet.org/congress-and-events/congress/

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