Oxidation of essential amino acids by the ovine gastrointestinal tract

Gerald Lobley; Xiangzhen Shen; Guowei Le; David Bremner; Eric Milne; Alexander Graham Calder; Susan Elizabeth Anderson; Ngaire Dennison

doi:10.1079/BJN2003831

Oxidation of essential amino acids by the ovine gastrointestinal tract

Gerald Lobley, Xiangzhen Shen, Guowei Le, David Bremner, Eric Milne, Alexander Graham Calder, Susan Elizabeth Anderson, Ngaire Dennison

The Rowett Institute of Nutrition and Health

Research output: Contribution to journal › Article › peer-review

57 Citations (Scopus)

Abstract

It is not known if the ruminant animal gastrointestinal tract (GIT) can oxidise essential amino acids (AA) other than leucine. Therefore, the oxidation of four essential AA (leucine, lysine, methionine and phenylalanine), supplied systemically as labelled 1-13C forms, was monitored across the mesenteric-drained viscera (MDV; small intestine) and portal-drained viscera (PDV; total GIT), as part of a Latin square design, in four wether sheep (35-45 kg) fed at 1.4 x maintenance. Oxidation was assessed primarily by appearance of 13CO2, corrected for sequestration of [13C]bicarbonate. The GIT contributed 25 % (P

Original language	English
Pages (from-to)	617-620
Number of pages	4
Journal	British Journal of Nutrition
Volume	89
Issue number	5
DOIs	https://doi.org/10.1079/BJN2003831
Publication status	Published - 1 May 2003

Keywords

Amino Acids, Essential
Analysis of Variance
Animals
Blood Specimen Collection
Digestive System
Intestine, Small
Leucine
Lysine
Male
Mesenteric Veins
Methionine
Oxidation-Reduction
Phenylalanine
Portal Vein
Sheep

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10.1079/BJN2003831

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title = "Oxidation of essential amino acids by the ovine gastrointestinal tract",

abstract = "It is not known if the ruminant animal gastrointestinal tract (GIT) can oxidise essential amino acids (AA) other than leucine. Therefore, the oxidation of four essential AA (leucine, lysine, methionine and phenylalanine), supplied systemically as labelled 1-13C forms, was monitored across the mesenteric-drained viscera (MDV; small intestine) and portal-drained viscera (PDV; total GIT), as part of a Latin square design, in four wether sheep (35-45 kg) fed at 1.4 x maintenance. Oxidation was assessed primarily by appearance of 13CO2, corrected for sequestration of [13C]bicarbonate. The GIT contributed 25 % (P",

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author = "Gerald Lobley and Xiangzhen Shen and Guowei Le and David Bremner and Eric Milne and Calder, {Alexander Graham} and Anderson, {Susan Elizabeth} and Ngaire Dennison",

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T1 - Oxidation of essential amino acids by the ovine gastrointestinal tract

AU - Lobley, Gerald

AU - Shen, Xiangzhen

AU - Le, Guowei

AU - Bremner, David

AU - Milne, Eric

AU - Calder, Alexander Graham

AU - Anderson, Susan Elizabeth

AU - Dennison, Ngaire

PY - 2003/5/1

Y1 - 2003/5/1

N2 - It is not known if the ruminant animal gastrointestinal tract (GIT) can oxidise essential amino acids (AA) other than leucine. Therefore, the oxidation of four essential AA (leucine, lysine, methionine and phenylalanine), supplied systemically as labelled 1-13C forms, was monitored across the mesenteric-drained viscera (MDV; small intestine) and portal-drained viscera (PDV; total GIT), as part of a Latin square design, in four wether sheep (35-45 kg) fed at 1.4 x maintenance. Oxidation was assessed primarily by appearance of 13CO2, corrected for sequestration of [13C]bicarbonate. The GIT contributed 25 % (P

AB - It is not known if the ruminant animal gastrointestinal tract (GIT) can oxidise essential amino acids (AA) other than leucine. Therefore, the oxidation of four essential AA (leucine, lysine, methionine and phenylalanine), supplied systemically as labelled 1-13C forms, was monitored across the mesenteric-drained viscera (MDV; small intestine) and portal-drained viscera (PDV; total GIT), as part of a Latin square design, in four wether sheep (35-45 kg) fed at 1.4 x maintenance. Oxidation was assessed primarily by appearance of 13CO2, corrected for sequestration of [13C]bicarbonate. The GIT contributed 25 % (P

KW - Amino Acids, Essential

KW - Analysis of Variance

KW - Animals

KW - Blood Specimen Collection

KW - Digestive System

KW - Intestine, Small

KW - Leucine

KW - Lysine

KW - Male

KW - Mesenteric Veins

KW - Methionine

KW - Oxidation-Reduction

KW - Phenylalanine

KW - Portal Vein

KW - Sheep

U2 - 10.1079/BJN2003831

DO - 10.1079/BJN2003831

M3 - Article

C2 - 12720582

SN - 0007-1145

VL - 89

SP - 617

EP - 620

JO - British Journal of Nutrition

JF - British Journal of Nutrition

IS - 5

ER -

Oxidation of essential amino acids by the ovine gastrointestinal tract

Abstract

Keywords

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