Oxidation of essential amino acids by the ovine gastrointestinal tract

Gerald Lobley, Xiangzhen Shen, Guowei Le, David Bremner, Eric Milne, Alexander Graham Calder, Susan Elizabeth Anderson, Ngaire Dennison

Research output: Contribution to journalArticlepeer-review

54 Citations (Scopus)


It is not known if the ruminant animal gastrointestinal tract (GIT) can oxidise essential amino acids (AA) other than leucine. Therefore, the oxidation of four essential AA (leucine, lysine, methionine and phenylalanine), supplied systemically as labelled 1-13C forms, was monitored across the mesenteric-drained viscera (MDV; small intestine) and portal-drained viscera (PDV; total GIT), as part of a Latin square design, in four wether sheep (35-45 kg) fed at 1.4 x maintenance. Oxidation was assessed primarily by appearance of 13CO2, corrected for sequestration of [13C]bicarbonate. The GIT contributed 25 % (P
Original languageEnglish
Pages (from-to)617-620
Number of pages4
JournalBritish Journal of Nutrition
Issue number5
Publication statusPublished - 1 May 2003


  • Amino Acids, Essential
  • Analysis of Variance
  • Animals
  • Blood Specimen Collection
  • Digestive System
  • Intestine, Small
  • Leucine
  • Lysine
  • Male
  • Mesenteric Veins
  • Methionine
  • Oxidation-Reduction
  • Phenylalanine
  • Portal Vein
  • Sheep


Dive into the research topics of 'Oxidation of essential amino acids by the ovine gastrointestinal tract'. Together they form a unique fingerprint.

Cite this