Parental occupation is a risk factor for childhood wheeze and asthma

N Tagiyeva, G Devereux, Sean Semple, A Sherriff, J Henderson, P Elias, Jon Ayres

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

The present birth-cohort study investigated whether childhood wheeze and asthma is associated with parental exposure to occupational sensitisers that cause asthma.Parental occupation from the Avon Longitudinal Study of Parents and Children was related to wheeze, asthma, ventilatory function, airway responsiveness and atopic sensitisation in children aged 0-102 months.Occupation was recorded for 11,193 mothers and 9,473 fathers ante-natally, and for 4,631 mothers and 5,315 fathers post-natally. Childhood respiratory outcomes were not associated with parental occupational exposure to diisocyanates, glues/resins, dyes, animal dust, solder, enzymes, and wood-dust. Maternal post-natal occupational exposure to latex and/or biocide/fungicides increased the likelihood of childhood wheeze and asthma. High levels of latex or biocide/fungicide exposure were associated with odds ratios of 1.26 [1.07-1.50] and 1.22 [1.02-2.05] respectively for wheezing up to 81 months. Combined maternal latex and biocide/fungicide exposures increased the likelihood of childhood wheeze (OR 1.22 [1.03-1.43]) and asthma. High paternal occupational flour dust exposure was associated with an increased likelihood of wheeze after 30 months (OR 2.31 [1.05-5.10]) and asthma by 91-months (OR 3.23 [1.34-7.79]).Maternal occupational exposure to latex and/or biocides and paternal exposure to flour dust increases the risk of childhood asthma. Further studies in this area are justified.
Original languageEnglish
Pages (from-to)987-993
Number of pages7
JournalEuropean Respiratory Journal
Volume35
Issue number5
Early online date19 Nov 2009
DOIs
Publication statusPublished - 2010

Fingerprint

Occupations
Asthma
Disinfectants
Latex
Occupational Exposure
Dust
Mothers
Flour
Fathers
Paternal Exposure
Maternal Exposure
Respiratory Sounds
Adhesives
Longitudinal Studies
Cohort Studies
Coloring Agents
Parents
Odds Ratio
Parturition
Enzymes

Keywords

  • children
  • flour
  • jobs
  • latex
  • parents
  • wheezing

Cite this

Tagiyeva, N., Devereux, G., Semple, S., Sherriff, A., Henderson, J., Elias, P., & Ayres, J. (2010). Parental occupation is a risk factor for childhood wheeze and asthma. European Respiratory Journal, 35(5), 987-993. https://doi.org/10.1183/09031936.00050009

Parental occupation is a risk factor for childhood wheeze and asthma. / Tagiyeva, N; Devereux, G; Semple, Sean; Sherriff, A; Henderson, J; Elias, P; Ayres, Jon.

In: European Respiratory Journal, Vol. 35, No. 5, 2010, p. 987-993.

Research output: Contribution to journalArticle

Tagiyeva, N, Devereux, G, Semple, S, Sherriff, A, Henderson, J, Elias, P & Ayres, J 2010, 'Parental occupation is a risk factor for childhood wheeze and asthma' European Respiratory Journal, vol. 35, no. 5, pp. 987-993. https://doi.org/10.1183/09031936.00050009
Tagiyeva, N ; Devereux, G ; Semple, Sean ; Sherriff, A ; Henderson, J ; Elias, P ; Ayres, Jon. / Parental occupation is a risk factor for childhood wheeze and asthma. In: European Respiratory Journal. 2010 ; Vol. 35, No. 5. pp. 987-993.
@article{8b49f440730949fbbe818d5ad3a2709b,
title = "Parental occupation is a risk factor for childhood wheeze and asthma",
abstract = "The present birth-cohort study investigated whether childhood wheeze and asthma is associated with parental exposure to occupational sensitisers that cause asthma.Parental occupation from the Avon Longitudinal Study of Parents and Children was related to wheeze, asthma, ventilatory function, airway responsiveness and atopic sensitisation in children aged 0-102 months.Occupation was recorded for 11,193 mothers and 9,473 fathers ante-natally, and for 4,631 mothers and 5,315 fathers post-natally. Childhood respiratory outcomes were not associated with parental occupational exposure to diisocyanates, glues/resins, dyes, animal dust, solder, enzymes, and wood-dust. Maternal post-natal occupational exposure to latex and/or biocide/fungicides increased the likelihood of childhood wheeze and asthma. High levels of latex or biocide/fungicide exposure were associated with odds ratios of 1.26 [1.07-1.50] and 1.22 [1.02-2.05] respectively for wheezing up to 81 months. Combined maternal latex and biocide/fungicide exposures increased the likelihood of childhood wheeze (OR 1.22 [1.03-1.43]) and asthma. High paternal occupational flour dust exposure was associated with an increased likelihood of wheeze after 30 months (OR 2.31 [1.05-5.10]) and asthma by 91-months (OR 3.23 [1.34-7.79]).Maternal occupational exposure to latex and/or biocides and paternal exposure to flour dust increases the risk of childhood asthma. Further studies in this area are justified.",
keywords = "children, flour, jobs, latex, parents, wheezing",
author = "N Tagiyeva and G Devereux and Sean Semple and A Sherriff and J Henderson and P Elias and Jon Ayres",
year = "2010",
doi = "10.1183/09031936.00050009",
language = "English",
volume = "35",
pages = "987--993",
journal = "European Respiratory Journal",
issn = "0903-1936",
publisher = "European Respiratory Society",
number = "5",

}

TY - JOUR

T1 - Parental occupation is a risk factor for childhood wheeze and asthma

AU - Tagiyeva, N

AU - Devereux, G

AU - Semple, Sean

AU - Sherriff, A

AU - Henderson, J

AU - Elias, P

AU - Ayres, Jon

PY - 2010

Y1 - 2010

N2 - The present birth-cohort study investigated whether childhood wheeze and asthma is associated with parental exposure to occupational sensitisers that cause asthma.Parental occupation from the Avon Longitudinal Study of Parents and Children was related to wheeze, asthma, ventilatory function, airway responsiveness and atopic sensitisation in children aged 0-102 months.Occupation was recorded for 11,193 mothers and 9,473 fathers ante-natally, and for 4,631 mothers and 5,315 fathers post-natally. Childhood respiratory outcomes were not associated with parental occupational exposure to diisocyanates, glues/resins, dyes, animal dust, solder, enzymes, and wood-dust. Maternal post-natal occupational exposure to latex and/or biocide/fungicides increased the likelihood of childhood wheeze and asthma. High levels of latex or biocide/fungicide exposure were associated with odds ratios of 1.26 [1.07-1.50] and 1.22 [1.02-2.05] respectively for wheezing up to 81 months. Combined maternal latex and biocide/fungicide exposures increased the likelihood of childhood wheeze (OR 1.22 [1.03-1.43]) and asthma. High paternal occupational flour dust exposure was associated with an increased likelihood of wheeze after 30 months (OR 2.31 [1.05-5.10]) and asthma by 91-months (OR 3.23 [1.34-7.79]).Maternal occupational exposure to latex and/or biocides and paternal exposure to flour dust increases the risk of childhood asthma. Further studies in this area are justified.

AB - The present birth-cohort study investigated whether childhood wheeze and asthma is associated with parental exposure to occupational sensitisers that cause asthma.Parental occupation from the Avon Longitudinal Study of Parents and Children was related to wheeze, asthma, ventilatory function, airway responsiveness and atopic sensitisation in children aged 0-102 months.Occupation was recorded for 11,193 mothers and 9,473 fathers ante-natally, and for 4,631 mothers and 5,315 fathers post-natally. Childhood respiratory outcomes were not associated with parental occupational exposure to diisocyanates, glues/resins, dyes, animal dust, solder, enzymes, and wood-dust. Maternal post-natal occupational exposure to latex and/or biocide/fungicides increased the likelihood of childhood wheeze and asthma. High levels of latex or biocide/fungicide exposure were associated with odds ratios of 1.26 [1.07-1.50] and 1.22 [1.02-2.05] respectively for wheezing up to 81 months. Combined maternal latex and biocide/fungicide exposures increased the likelihood of childhood wheeze (OR 1.22 [1.03-1.43]) and asthma. High paternal occupational flour dust exposure was associated with an increased likelihood of wheeze after 30 months (OR 2.31 [1.05-5.10]) and asthma by 91-months (OR 3.23 [1.34-7.79]).Maternal occupational exposure to latex and/or biocides and paternal exposure to flour dust increases the risk of childhood asthma. Further studies in this area are justified.

KW - children

KW - flour

KW - jobs

KW - latex

KW - parents

KW - wheezing

U2 - 10.1183/09031936.00050009

DO - 10.1183/09031936.00050009

M3 - Article

VL - 35

SP - 987

EP - 993

JO - European Respiratory Journal

JF - European Respiratory Journal

SN - 0903-1936

IS - 5

ER -