Partial recovery from amnesia following bilateral surgical fornix transection is correlated with cortical plasticity

N K Mazarakis, F Summers, A D Murray, G D Waiter, I P Fouyas

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2 Citations (Scopus)


We report a case of an interventricular ependymoma which was surgically removed but also required bilateral transection of the fornices resulting in memory impairment which gradually improved. Functional MR images using a memory paradigm showed that recovery correlated with cortical plasticity involving activation of the orbitofrontal cortex and the middle temporal gyrus.
Original languageEnglish
Pages (from-to)658-661
Number of pages4
JournalBritish Journal of Neurosurgery
Issue number5
Publication statusPublished - Oct 2011



  • adult
  • amnesia
  • cerebral ventricle neoplasms
  • ependymoma
  • fornix, brain
  • humans
  • magnetic resonance imaging
  • male
  • neuronal plasticity
  • neuropsychological tests
  • postoperative complications
  • prefrontal cortex
  • recovery of function
  • treatment outcome
  • neuropsychology
  • memory
  • tumour

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