Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers

results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Nasim Mavaddat, Daniel Barrowdale, Irene L Andrulis, Susan M Domchek, Diana Eccles, Heli Nevanlinna, Susan J Ramus, Amanda Spurdle, Mark Robson, Mark Sherman, Anna Marie Mulligan, Fergus J Couch, Christoph Engel, Lesley McGuffog, Sue Healey, Olga M Sinilnikova, Melissa C Southey, Mary Beth Terry, David Goldgar, Frances O'Malley & 31 others Esther M John, Ramunas Janavicius, Laima Tihomirova, Thomas V O Hansen, Finn C Nielsen, Ana Osorio, Alexandra Stavropoulou, Javier Benítez, Siranoush Manoukian, Bernard Peissel, Monica Barile, Sara Volorio, Barbara Pasini, Riccardo Dolcetti, Anna Laura Putignano, Laura Ottini, Paolo Radice, Ute Hamann, Muhammad U Rashid, Frans B Hogervorst, Mieke Kriege, Rob B van der Luijt, Susan Peock, Debra Frost, D Gareth Evans, Carole Brewer, Lisa Walker, Mark T Rogers, Lucy E Side, HEBON, Zosia Miedzybrodzka

Research output: Contribution to journalArticle

249 Citations (Scopus)

Abstract

Previously, small studies have found that BRCA1 and BRCA2 breast tumors differ in their pathology. Analysis of larger datasets of mutation carriers should allow further tumor characterization.
Original languageEnglish
Pages (from-to)134-147
Number of pages14
JournalCancer Epidemiology, Biomarkers and Prevention
Volume21
Issue number1
Early online date5 Dec 2011
DOIs
Publication statusPublished - 21 Jan 2012

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Ovarian Neoplasms
Research Personnel
Pathology
Breast Neoplasms
Mutation
Neoplasms
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Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers : results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). / Mavaddat, Nasim; Barrowdale, Daniel; Andrulis, Irene L; Domchek, Susan M; Eccles, Diana; Nevanlinna, Heli; Ramus, Susan J; Spurdle, Amanda; Robson, Mark; Sherman, Mark; Mulligan, Anna Marie; Couch, Fergus J; Engel, Christoph; McGuffog, Lesley; Healey, Sue; Sinilnikova, Olga M; Southey, Melissa C; Terry, Mary Beth; Goldgar, David; O'Malley, Frances; John, Esther M; Janavicius, Ramunas; Tihomirova, Laima; Hansen, Thomas V O; Nielsen, Finn C; Osorio, Ana; Stavropoulou, Alexandra; Benítez, Javier; Manoukian, Siranoush; Peissel, Bernard; Barile, Monica; Volorio, Sara; Pasini, Barbara; Dolcetti, Riccardo; Putignano, Anna Laura; Ottini, Laura; Radice, Paolo; Hamann, Ute; Rashid, Muhammad U; Hogervorst, Frans B; Kriege, Mieke; van der Luijt, Rob B; Peock, Susan; Frost, Debra; Evans, D Gareth; Brewer, Carole; Walker, Lisa; Rogers, Mark T; Side, Lucy E; HEBON ; Miedzybrodzka, Zosia.

In: Cancer Epidemiology, Biomarkers and Prevention, Vol. 21, No. 1, 21.01.2012, p. 134-147.

Research output: Contribution to journalArticle

Mavaddat, N, Barrowdale, D, Andrulis, IL, Domchek, SM, Eccles, D, Nevanlinna, H, Ramus, SJ, Spurdle, A, Robson, M, Sherman, M, Mulligan, AM, Couch, FJ, Engel, C, McGuffog, L, Healey, S, Sinilnikova, OM, Southey, MC, Terry, MB, Goldgar, D, O'Malley, F, John, EM, Janavicius, R, Tihomirova, L, Hansen, TVO, Nielsen, FC, Osorio, A, Stavropoulou, A, Benítez, J, Manoukian, S, Peissel, B, Barile, M, Volorio, S, Pasini, B, Dolcetti, R, Putignano, AL, Ottini, L, Radice, P, Hamann, U, Rashid, MU, Hogervorst, FB, Kriege, M, van der Luijt, RB, Peock, S, Frost, D, Evans, DG, Brewer, C, Walker, L, Rogers, MT, Side, LE, HEBON & Miedzybrodzka, Z 2012, 'Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)', Cancer Epidemiology, Biomarkers and Prevention, vol. 21, no. 1, pp. 134-147. https://doi.org/10.1158/1055-9965.EPI-11-0775
Mavaddat, Nasim ; Barrowdale, Daniel ; Andrulis, Irene L ; Domchek, Susan M ; Eccles, Diana ; Nevanlinna, Heli ; Ramus, Susan J ; Spurdle, Amanda ; Robson, Mark ; Sherman, Mark ; Mulligan, Anna Marie ; Couch, Fergus J ; Engel, Christoph ; McGuffog, Lesley ; Healey, Sue ; Sinilnikova, Olga M ; Southey, Melissa C ; Terry, Mary Beth ; Goldgar, David ; O'Malley, Frances ; John, Esther M ; Janavicius, Ramunas ; Tihomirova, Laima ; Hansen, Thomas V O ; Nielsen, Finn C ; Osorio, Ana ; Stavropoulou, Alexandra ; Benítez, Javier ; Manoukian, Siranoush ; Peissel, Bernard ; Barile, Monica ; Volorio, Sara ; Pasini, Barbara ; Dolcetti, Riccardo ; Putignano, Anna Laura ; Ottini, Laura ; Radice, Paolo ; Hamann, Ute ; Rashid, Muhammad U ; Hogervorst, Frans B ; Kriege, Mieke ; van der Luijt, Rob B ; Peock, Susan ; Frost, Debra ; Evans, D Gareth ; Brewer, Carole ; Walker, Lisa ; Rogers, Mark T ; Side, Lucy E ; HEBON ; Miedzybrodzka, Zosia. / Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers : results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). In: Cancer Epidemiology, Biomarkers and Prevention. 2012 ; Vol. 21, No. 1. pp. 134-147.
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