Patient-reported adverse events under asthma therapy: a community pharmacy-based survey

L. Laforest, E. Van Ganse, G. Devouassoux, Liesl Marten Osman, G. Bauguil, G. Chamba

    Research output: Contribution to journalArticle

    3 Citations (Scopus)

    Abstract

    The characteristics of patients who report adverse events (AEs) attributed to asthma therapy have been little investigated. Asthma patients aged 18-50 years were surveyed in pharmacies. Patients completed a questionnaire linked to computerized records of dispensed medications. Patients reported all AEs that they attributed to asthma therapy. The correlates of reporting 2+ AEs were identified. Almost 59% of the 1,351 patients (mean age: 37, 56% females) attributed AEs to asthma therapy, and 35% at least two. Most common AEs included tiredness (21.8%) and palpitations (21.1%). Poor asthma control and perception of asthma as a handicap were the major correlates of reporting 2+ AEs (odds ratio (OR) = 2.5, 95% confidence interval (CI) =[1.7-3.7] and OR = 1.9, 95% CI =[1.4-2.5]). Other significant correlates included age 430 years, female gender, and receiving psychotropic therapy. Inadequate control may partly account for AEs attributed by patients to asthma therapy. Improving patients' education may help to improve acceptability of asthma therapy.

    Original languageEnglish
    Pages (from-to)167-172
    Number of pages6
    JournalBritish Journal of Clinical Pharmacology
    Volume82
    Issue number2
    DOIs
    Publication statusPublished - Aug 2007

    Keywords

    • inhaled corticosteroids
    • poor compliance
    • adults
    • adherence
    • outcomes
    • quality
    • gender
    • risk
    • care

    Cite this

    Laforest, L., Van Ganse, E., Devouassoux, G., Osman, L. M., Bauguil, G., & Chamba, G. (2007). Patient-reported adverse events under asthma therapy: a community pharmacy-based survey. British Journal of Clinical Pharmacology, 82(2), 167-172. https://doi.org/10.1038/sj.clpt.6100224

    Patient-reported adverse events under asthma therapy : a community pharmacy-based survey. / Laforest, L.; Van Ganse, E.; Devouassoux, G.; Osman, Liesl Marten; Bauguil, G.; Chamba, G.

    In: British Journal of Clinical Pharmacology, Vol. 82, No. 2, 08.2007, p. 167-172.

    Research output: Contribution to journalArticle

    Laforest, L, Van Ganse, E, Devouassoux, G, Osman, LM, Bauguil, G & Chamba, G 2007, 'Patient-reported adverse events under asthma therapy: a community pharmacy-based survey', British Journal of Clinical Pharmacology, vol. 82, no. 2, pp. 167-172. https://doi.org/10.1038/sj.clpt.6100224
    Laforest, L. ; Van Ganse, E. ; Devouassoux, G. ; Osman, Liesl Marten ; Bauguil, G. ; Chamba, G. / Patient-reported adverse events under asthma therapy : a community pharmacy-based survey. In: British Journal of Clinical Pharmacology. 2007 ; Vol. 82, No. 2. pp. 167-172.
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    abstract = "The characteristics of patients who report adverse events (AEs) attributed to asthma therapy have been little investigated. Asthma patients aged 18-50 years were surveyed in pharmacies. Patients completed a questionnaire linked to computerized records of dispensed medications. Patients reported all AEs that they attributed to asthma therapy. The correlates of reporting 2+ AEs were identified. Almost 59{\%} of the 1,351 patients (mean age: 37, 56{\%} females) attributed AEs to asthma therapy, and 35{\%} at least two. Most common AEs included tiredness (21.8{\%}) and palpitations (21.1{\%}). Poor asthma control and perception of asthma as a handicap were the major correlates of reporting 2+ AEs (odds ratio (OR) = 2.5, 95{\%} confidence interval (CI) =[1.7-3.7] and OR = 1.9, 95{\%} CI =[1.4-2.5]). Other significant correlates included age 430 years, female gender, and receiving psychotropic therapy. Inadequate control may partly account for AEs attributed by patients to asthma therapy. Improving patients' education may help to improve acceptability of asthma therapy.",
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