Photoperiodic programming of body weight through the neuroendocrine hypothalamus

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50 Citations (Scopus)

Abstract

The photoperiodic mammal undergoes quite remarkable changes in physiology as part of its natural adaptations to seasonal fluctuations in the environment. Changes in energy balance and body weight are among these adaptations. In some seasonal mammals, such as the Siberian hamster (Phodopus sungorus), these changes in body weight have been explored in detail, and there is evidence for tightly controlled systems of energy balance that are coordinated by photoperiod acting via the temporal pattern of melatonin secretion from the pineal gland. The pathways and systems involved appear to be quite distinct from the hypothalamic pathways identified to regulate energy balance in studies of both mice and rats thus far. Instead it appears that in the Siberian hamster a tightly regulated system under the control of photoperiod is able to reset the tone of the systems involved in energy balance regulation. Understanding how photoperiod and melatonin act within the hypothalamus to regulate energy balance offers potentially fundamental and important new insights into the control of energy balance. This review describes the current state of our knowledge.

Original languageEnglish
Pages (from-to)27-34
Number of pages8
JournalJournal of Endocrinology
Volume177
Issue number1
Publication statusPublished - Apr 2003

Keywords

  • hamster phodopus-sungorus
  • male Siberian hamster
  • Djungarian hamster
  • suprachiasmatic nucleus
  • food-intake
  • gene-expression
  • pars tuberalis
  • melatonin
  • lesions
  • cycle

Cite this

@article{ff1577bececa4adfae717b738211e8bd,
title = "Photoperiodic programming of body weight through the neuroendocrine hypothalamus",
abstract = "The photoperiodic mammal undergoes quite remarkable changes in physiology as part of its natural adaptations to seasonal fluctuations in the environment. Changes in energy balance and body weight are among these adaptations. In some seasonal mammals, such as the Siberian hamster (Phodopus sungorus), these changes in body weight have been explored in detail, and there is evidence for tightly controlled systems of energy balance that are coordinated by photoperiod acting via the temporal pattern of melatonin secretion from the pineal gland. The pathways and systems involved appear to be quite distinct from the hypothalamic pathways identified to regulate energy balance in studies of both mice and rats thus far. Instead it appears that in the Siberian hamster a tightly regulated system under the control of photoperiod is able to reset the tone of the systems involved in energy balance regulation. Understanding how photoperiod and melatonin act within the hypothalamus to regulate energy balance offers potentially fundamental and important new insights into the control of energy balance. This review describes the current state of our knowledge.",
keywords = "hamster phodopus-sungorus, male Siberian hamster, Djungarian hamster, suprachiasmatic nucleus, food-intake, gene-expression, pars tuberalis, melatonin, lesions, cycle",
author = "Morgan, {Peter John} and Alexander Ross and Julian Mercer and Perry Barrett",
year = "2003",
month = "4",
language = "English",
volume = "177",
pages = "27--34",
journal = "Journal of Endocrinology",
issn = "0022-0795",
publisher = "Society for Endocrinology",
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TY - JOUR

T1 - Photoperiodic programming of body weight through the neuroendocrine hypothalamus

AU - Morgan, Peter John

AU - Ross, Alexander

AU - Mercer, Julian

AU - Barrett, Perry

PY - 2003/4

Y1 - 2003/4

N2 - The photoperiodic mammal undergoes quite remarkable changes in physiology as part of its natural adaptations to seasonal fluctuations in the environment. Changes in energy balance and body weight are among these adaptations. In some seasonal mammals, such as the Siberian hamster (Phodopus sungorus), these changes in body weight have been explored in detail, and there is evidence for tightly controlled systems of energy balance that are coordinated by photoperiod acting via the temporal pattern of melatonin secretion from the pineal gland. The pathways and systems involved appear to be quite distinct from the hypothalamic pathways identified to regulate energy balance in studies of both mice and rats thus far. Instead it appears that in the Siberian hamster a tightly regulated system under the control of photoperiod is able to reset the tone of the systems involved in energy balance regulation. Understanding how photoperiod and melatonin act within the hypothalamus to regulate energy balance offers potentially fundamental and important new insights into the control of energy balance. This review describes the current state of our knowledge.

AB - The photoperiodic mammal undergoes quite remarkable changes in physiology as part of its natural adaptations to seasonal fluctuations in the environment. Changes in energy balance and body weight are among these adaptations. In some seasonal mammals, such as the Siberian hamster (Phodopus sungorus), these changes in body weight have been explored in detail, and there is evidence for tightly controlled systems of energy balance that are coordinated by photoperiod acting via the temporal pattern of melatonin secretion from the pineal gland. The pathways and systems involved appear to be quite distinct from the hypothalamic pathways identified to regulate energy balance in studies of both mice and rats thus far. Instead it appears that in the Siberian hamster a tightly regulated system under the control of photoperiod is able to reset the tone of the systems involved in energy balance regulation. Understanding how photoperiod and melatonin act within the hypothalamus to regulate energy balance offers potentially fundamental and important new insights into the control of energy balance. This review describes the current state of our knowledge.

KW - hamster phodopus-sungorus

KW - male Siberian hamster

KW - Djungarian hamster

KW - suprachiasmatic nucleus

KW - food-intake

KW - gene-expression

KW - pars tuberalis

KW - melatonin

KW - lesions

KW - cycle

M3 - Article

VL - 177

SP - 27

EP - 34

JO - Journal of Endocrinology

JF - Journal of Endocrinology

SN - 0022-0795

IS - 1

ER -