Photoperiodic signalling through the melatonin receptor turns full circle

Peter John Morgan, David Grey Hazlerigg

Research output: Contribution to journalLiterature review

35 Citations (Scopus)

Abstract

Photoperiod exerts profound influence on the physiology of mammals through the action of melatonin on the neuroendocrine system. Over the last 20 years, studies have moved away from a melatonin receptor-focused approach to understanding how photoperiod regulates neuroendocrine activity through studies of downstream effects on gene expression. This paper reviews the recent progress made in our understanding of the effects of photoperiod on gene expression in the hypothalamus, and considers how this new information can be reconciled with the species-specific location of melatonin receptors.

Original languageEnglish
Pages (from-to)820-826
Number of pages7
JournalJournal of Neuroendocrinology
Volume20
Issue number6
DOIs
Publication statusPublished - Jun 2008

Keywords

  • melatonin
  • thyroid
  • retinoid
  • parstuberalis
  • kisspeptin
  • prolactin
  • type-2 deiodinase gene
  • ovine pars tuberalis
  • luteinizing-hormone secretion
  • inactivating enzyme genes
  • male Syrian-hamsters
  • retinoid-x-receptor
  • mediobasal hypothalamus
  • arcuate nucleus
  • pituitary-gland
  • binding-sites

Cite this

Photoperiodic signalling through the melatonin receptor turns full circle. / Morgan, Peter John; Hazlerigg, David Grey.

In: Journal of Neuroendocrinology, Vol. 20, No. 6, 06.2008, p. 820-826.

Research output: Contribution to journalLiterature review

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