Physical fitness and lifetime cognitive change

I. J. deary, Lawrence Jeffrey Whalley, G. D. Batty, J. M. Starr

    Research output: Contribution to journalArticle

    90 Citations (Scopus)

    Abstract

    Objective: To test the hypothesis that physical fitness is associated with more successful cognitive aging. Methods: Surviving participants (N = 460) of the Scottish Mental Survey of 1932 were tested on the same general cognitive test at age 11 and 79 years. Measures of grip strength, 6-meter walk time, and lung function (forced expiratory volume from the lungs in 1 second [FEV1]) were assessed at age 79 years. Results: A latent physical fitness trait, derived by principal components analysis of the three fitness measures, was significantly associated with successful cognitive aging. Cognitive score at age 11, sex, social class, and APOE-epsilon 4 genotype were included as covariables. Higher childhood IQ was associated with better lung function in old age. Conclusions: Physical fitness is associated with cognitive reserve. Intervention studies aimed at making older people fitter are good candidates to improve cognitive aging.

    Original languageEnglish
    Pages (from-to)1195-1200
    Number of pages5
    JournalNeurology
    Volume67
    Issue number7
    DOIs
    Publication statusPublished - Oct 2006

    Keywords

    • SCOTTISH MENTAL SURVEY
    • CHILDHOOD IQ
    • PERFORMANCE
    • SMOKING
    • ABILITY
    • AGE
    • ASSOCIATIONS
    • INTELLIGENCE
    • BIOMARKERS
    • ADULTHOOD

    Cite this

    deary, I. J., Whalley, L. J., Batty, G. D., & Starr, J. M. (2006). Physical fitness and lifetime cognitive change. Neurology, 67(7), 1195-1200. https://doi.org/10.1212/01.wnl.0000238520.06958.6a