Population-Genetics of Mycobacterium Tuberculosis Complex in Scotland Analyzed by Pulsed Field Gel Electrophoresis

Shona Olson, Ken J. Forbes, B WATT, Thomas Hugh Pennington

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The results of typing of 121 strains in the Mycobacterium tuberculosis complex by PFGE are presented. Every isolate from patients in Scotland over a S-month period for M. tuberculosis and for 1 year for M. bovis were included along with several laboratory strains including those of BCG. The PFGE results suggest that the population structure of all the strains in this complex is distinctly simple with limited genetic diversity and also suggest that M. bovis is not a distinct species.

Original languageEnglish
Pages (from-to)153-160
Number of pages8
JournalEpidemiology and Infection
Issue number1
Publication statusPublished - Feb 1995


  • restriction fragment patterns
  • deoxyribonucleic-acid relatedness
  • endonuclease analysis
  • DNA
  • strains
  • identification
  • seals
  • heterogeneity
  • polymorphism

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