Potential role of probiotic bacteria in the treatment and prevention of localised candidosis

Daniela Mailänder-Sánchez, Jeanette Wagener, Martin Schaller

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The extensive use of immunosuppressive therapies in recent years has increased the number of patients prone to or actually suffering from localised candidosis. As Candida species gain increasing resistance towards common antifungal drugs, new strategies are needed to prevent and treat infections caused by these pathogens. Probiotic bacteria have been in vogue in the past two decades. More and more dairy products containing such organisms offer promising potential beneficial effects on human health and well-being. Because of the ability of probiotic bacteria to inhibit the growth of pathogens and to modulate human immune responses, these bacteria could provide new possibilities in antifungal therapy. We summarise the recent findings concerning the usefulness of probiotic treatment in localised candidosis, as well as discussing possible risks of probiotic treatment and highlighting the molecular mechanisms that are believed to contribute to probiotic effects.
Original languageEnglish
Pages (from-to)17-26
Number of pages10
JournalMycoses
Volume55
Issue number1
Early online date14 Jun 2011
DOIs
Publication statusPublished - Jan 2012

Keywords

  • candidosis
  • probiotic
  • lactobacilli

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