TY - JOUR
T1 - Predictive and prognostic value of LSP1 rs3817198 in sporadic breast cancer in northeastern population of Iran
AU - Afzaljavan, Fahimeh
AU - Moezzi, Atefeh
AU - Vahednia, Elham
AU - Khorshid Shamshiri, Asma
AU - Vakili, Fatemeh
AU - Homaei Shandiz, Fatemeh
AU - Pasdar, Alireza
N1 - Acknowledgements:
The authors thank all participants in this research. We would also like to thank the Student Research Committee, Mashhad University of Medical Sciences and Omid hospital (Mashhhad, Iran) to support the project.
Funding:
This work was financially supported by Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran, under Grant 961686.
PY - 2020/10/31
Y1 - 2020/10/31
N2 - Being the most common malignancy affecting patient's lifetime worldwide, the diagnosis of breast cancer especially in its early stages is of paramount importance (Wang, 2017). It has been reported that about 22.6 in 100,000 Iranian women would develop the primary breast cancer during their lifetime (Jazayeri et al., 2015). As a heterogeneous disease, which could be influenced through genetic or epigenetic mechanisms as well as environmental risk factors, characterization and treatment of breast cancer could be extremely demanding (Chen et al., 2011; Turnbull et al., 2011; Byler et al., 2014). Therefore, recent studies have been emphasizing on finding the potential risk factors contributing to the development, progression and response to the therapy of the disease (Ambrosone et al., 2015).
AB - Being the most common malignancy affecting patient's lifetime worldwide, the diagnosis of breast cancer especially in its early stages is of paramount importance (Wang, 2017). It has been reported that about 22.6 in 100,000 Iranian women would develop the primary breast cancer during their lifetime (Jazayeri et al., 2015). As a heterogeneous disease, which could be influenced through genetic or epigenetic mechanisms as well as environmental risk factors, characterization and treatment of breast cancer could be extremely demanding (Chen et al., 2011; Turnbull et al., 2011; Byler et al., 2014). Therefore, recent studies have been emphasizing on finding the potential risk factors contributing to the development, progression and response to the therapy of the disease (Ambrosone et al., 2015).
UR - http://www.scopus.com/inward/record.url?scp=85089559979&partnerID=8YFLogxK
U2 - 10.1016/j.yexmp.2020.104514
DO - 10.1016/j.yexmp.2020.104514
M3 - Article
C2 - 32738313
VL - 116
JO - Experimental and molecular pathology
JF - Experimental and molecular pathology
SN - 0014-4800
M1 - 104514
ER -
