Abstract
Background People living with colorectal cancer are at risk of anxiety and depression. We investigated what factors were most highly associated with these.
Methods Four hundred and ninety-six people with colorectal cancer completed the Hospital Anxiety and Depression Scale (HADS). Data on functioning, symptoms, illness perceptions and social difficulties were collected by questionnaire. Casenote-identified disease, treatment and co-morbidity data were
recorded. Multiple logistic regression identified factors independently predictive of anxiety and depression caseness.
Results Self-reported history of anxiety/depression predicted anxiety but not depression caseness. Depression caseness predicted anxiety caseness (p =0.043), as did poorer selfreported
cognitive functioning (p =0.001), dyspnoea (p = 0.015) or diarrhoea (p =0.021), reporting a high negative life and emotional impact (p <0.001) and having difficulties with finance (p =0.007). Having neo-adjuvant radiotherapy increased the odds of depression caseness (p =0.007), as did
poorer physical (p =0.007), cognitive (p <0.001) and social (p <0.001) functioning, having constipation (p =0.011), reporting a high negative life and emotional impact (p < 0.001), having difficulties with personal care (p =0.022) and communicating with others (p =0.014).
Conclusion Levels of anxiety caseness were similar to those of non-clinical samples, but depression caseness was higher, particularly in those who had received neo-adjuvant radiotherapy. Most factors associated with possible or probable depression may be modified with appropriate intervention.
Methods Four hundred and ninety-six people with colorectal cancer completed the Hospital Anxiety and Depression Scale (HADS). Data on functioning, symptoms, illness perceptions and social difficulties were collected by questionnaire. Casenote-identified disease, treatment and co-morbidity data were
recorded. Multiple logistic regression identified factors independently predictive of anxiety and depression caseness.
Results Self-reported history of anxiety/depression predicted anxiety but not depression caseness. Depression caseness predicted anxiety caseness (p =0.043), as did poorer selfreported
cognitive functioning (p =0.001), dyspnoea (p = 0.015) or diarrhoea (p =0.021), reporting a high negative life and emotional impact (p <0.001) and having difficulties with finance (p =0.007). Having neo-adjuvant radiotherapy increased the odds of depression caseness (p =0.007), as did
poorer physical (p =0.007), cognitive (p <0.001) and social (p <0.001) functioning, having constipation (p =0.011), reporting a high negative life and emotional impact (p < 0.001), having difficulties with personal care (p =0.022) and communicating with others (p =0.014).
Conclusion Levels of anxiety caseness were similar to those of non-clinical samples, but depression caseness was higher, particularly in those who had received neo-adjuvant radiotherapy. Most factors associated with possible or probable depression may be modified with appropriate intervention.
Original language | English |
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Pages (from-to) | 307-314 |
Number of pages | 8 |
Journal | Supportive Care in Cancer |
Volume | 22 |
Issue number | 2 |
Early online date | 1 Oct 2013 |
DOIs | |
Publication status | Published - Feb 2014 |
Keywords
- anxiety
- depression
- colorectal cancer