OBJECTIVE: To determine the contribution of preeclampsia toward preterm birth in primiparous women.
METHODS: This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.
RESULTS: A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.
CONCLUSION: Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.
- Case–control study
- gestational hypertension
- perinatal morbidity and mortality