Preeclampsia and preterm delivery: A population-based case–control study

Emma L. Davies, Jacqueline S. Bell, Sohinee Bhattacharya

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Abstract

OBJECTIVE: To determine the contribution of preeclampsia toward preterm birth in primiparous women.

METHODS: This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.

RESULTS: A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.

CONCLUSION: Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.

Original languageEnglish
Pages (from-to)510-519
Number of pages10
JournalHypertension in Pregnancy
Volume35
Issue number4
Early online date20 Jun 2016
DOIs
Publication statusPublished - 2016

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Keywords

  • Case–control study
  • gestational hypertension
  • perinatal morbidity and mortality
  • preeclampsia

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