Preeclampsia and preterm delivery: A population-based case–control study

Emma L. Davies; Jacqueline S. Bell; Sohinee Bhattacharya

doi:10.1080/10641955.2016.1190846

Preeclampsia and preterm delivery: A population-based case–control study

Emma L. Davies, Jacqueline S. Bell, Sohinee Bhattacharya

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20 Citations (Scopus)

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Abstract

OBJECTIVE: To determine the contribution of preeclampsia toward preterm birth in primiparous women.

METHODS: This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.

RESULTS: A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.

CONCLUSION: Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.

Original language	English
Pages (from-to)	510-519
Number of pages	10
Journal	Hypertension in Pregnancy
Volume	35
Issue number	4
Early online date	20 Jun 2016
DOIs	https://doi.org/10.1080/10641955.2016.1190846
Publication status	Published - 2016

Keywords

Case–control study
gestational hypertension
perinatal morbidity and mortality
preeclampsia

Access to Document

10.1080/10641955.2016.1190846Licence: Unspecified

Accepted Manuscript
This is an Accepted Manuscript of an article published by Taylor & Francis in Hypertension in Pregnancy on 20th June 2016, available online: http://www.tandfonline.com/10.1080/10641955.2016.1190846
Accepted author manuscript, 35.9 KBLicence: Unspecified

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Davies, E. L., Bell, J. S., & Bhattacharya, S. (2016). Preeclampsia and preterm delivery: A population-based case–control study. Hypertension in Pregnancy, 35(4), 510-519. https://doi.org/10.1080/10641955.2016.1190846

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abstract = "OBJECTIVE: To determine the contribution of preeclampsia toward preterm birth in primiparous women.METHODS: This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.RESULTS: A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.CONCLUSION: Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.",

keywords = "Case–control study, gestational hypertension, perinatal morbidity and mortality, preeclampsia",

author = "Davies, {Emma L.} and Bell, {Jacqueline S.} and Sohinee Bhattacharya",

note = "Funding The data extraction was supported by a consultancy grant from Ferring and March of Dimes. Acknowledgements The authors would like to thank the Aberdeen University statistics team for the statistical advice provided and the data management team for the data extraction.",

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N2 - OBJECTIVE: To determine the contribution of preeclampsia toward preterm birth in primiparous women.METHODS: This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.RESULTS: A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.CONCLUSION: Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.

AB - OBJECTIVE: To determine the contribution of preeclampsia toward preterm birth in primiparous women.METHODS: This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.RESULTS: A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.CONCLUSION: Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.

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