Abstract
OBJECTIVE: To determine the contribution of preeclampsia toward preterm birth in primiparous women.
METHODS: This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.
RESULTS: A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.
CONCLUSION: Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.
| Original language | English |
|---|---|
| Pages (from-to) | 510-519 |
| Number of pages | 10 |
| Journal | Hypertension in Pregnancy |
| Volume | 35 |
| Issue number | 4 |
| Early online date | 20 Jun 2016 |
| DOIs | |
| Publication status | Published - 2016 |
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Keywords
- Case–control study
- gestational hypertension
- perinatal morbidity and mortality
- preeclampsia
Cite this
Preeclampsia and preterm delivery : A population-based case–control study. / Davies, Emma L.; Bell, Jacqueline S.; Bhattacharya, Sohinee.
In: Hypertension in Pregnancy, Vol. 35, No. 4, 2016, p. 510-519.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Preeclampsia and preterm delivery
T2 - A population-based case–control study
AU - Davies, Emma L.
AU - Bell, Jacqueline S.
AU - Bhattacharya, Sohinee
N1 - Funding The data extraction was supported by a consultancy grant from Ferring and March of Dimes. Acknowledgements The authors would like to thank the Aberdeen University statistics team for the statistical advice provided and the data management team for the data extraction.
PY - 2016
Y1 - 2016
N2 - OBJECTIVE: To determine the contribution of preeclampsia toward preterm birth in primiparous women.METHODS: This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.RESULTS: A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.CONCLUSION: Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.
AB - OBJECTIVE: To determine the contribution of preeclampsia toward preterm birth in primiparous women.METHODS: This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.RESULTS: A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.CONCLUSION: Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.
KW - Case–control study
KW - gestational hypertension
KW - perinatal morbidity and mortality
KW - preeclampsia
U2 - 10.1080/10641955.2016.1190846
DO - 10.1080/10641955.2016.1190846
M3 - Article
C2 - 27322489
VL - 35
SP - 510
EP - 519
JO - Hypertension in Pregnancy
JF - Hypertension in Pregnancy
SN - 1064-1955
IS - 4
ER -