Abstract
OBJECTIVE: To determine the contribution of preeclampsia toward preterm birth in primiparous women.
METHODS: This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.
RESULTS: A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.
CONCLUSION: Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.
Original language | English |
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Pages (from-to) | 510-519 |
Number of pages | 10 |
Journal | Hypertension in Pregnancy |
Volume | 35 |
Issue number | 4 |
Early online date | 20 Jun 2016 |
DOIs | |
Publication status | Published - 2016 |
Keywords
- Case–control study
- gestational hypertension
- perinatal morbidity and mortality
- preeclampsia