Preliminary comparison of the rupture of human and rabbit anterior cruciate ligaments

Godfrey Azangwe, K. J. Mathias, D. Marshall

    Research output: Contribution to journalArticle

    13 Citations (Scopus)

    Abstract

    Objective. This study was aimed at examining ruptures of the human anterior cruciate ligaments by scanning electron microscopy and video imaging and comparing the appearance of the rupture surfaces with those from rabbit anterior cruciate ligaments.

    Design. The specimens were tested to failure as femur-anterior cruciate ligament-tibia complexes using an Instron 8511 materials testing machine.

    Background. Rupture of the anterior cruciate ligament is a major clinical problem. leading to instability of the knee joint. Due to the frequency and potential severity of the injuries., a need still exists for information on the biomechanical properties of ligaments under loading conditions, which occur at the time of trauma.

    Methods. Four human femur-anterior cruciate ligament-tibia complexes were loaded to failure at a displacement rate of 0.008 m/s. Video recordings of the tests were used to study the progress of the ruptures and to compare the modes of failure of the ligaments, Scanning electron microscopy was employed to study the appearance of collagen fibres at the rupture surfaces.

    Results. The modes of failure of the rabbit anterior cruciate ligament and appearance of the rupture surfaces were similar to those of the human anterior cruciate ligaments.

    Conclusion. The rabbit anterior cruciate ligament provides a model for investigating failure of the human ligament during trauma.

    Original languageEnglish
    Pages (from-to)913-917
    Number of pages4
    JournalClinical Biomechanics
    Volume16
    Issue number10
    DOIs
    Publication statusPublished - 2001

    Keywords

    • anterior cruciate ligament
    • rupture
    • scanning electron microscopy
    • mechanical testing
    • fracture surface
    • KNEE LIGAMENTS
    • TIBIA COMPLEX
    • FAILURE

    Cite this

    Preliminary comparison of the rupture of human and rabbit anterior cruciate ligaments. / Azangwe, Godfrey; Mathias, K. J.; Marshall, D.

    In: Clinical Biomechanics, Vol. 16, No. 10, 2001, p. 913-917.

    Research output: Contribution to journalArticle

    Azangwe, Godfrey ; Mathias, K. J. ; Marshall, D. / Preliminary comparison of the rupture of human and rabbit anterior cruciate ligaments. In: Clinical Biomechanics. 2001 ; Vol. 16, No. 10. pp. 913-917.
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