Prevalence of vitamin D deficiency in healthy Iranian children: A systematic review and meta-analysis

Maryam Jazayeri, Yousef Moradi, Arezoo Rasti, Manouchehr Nakhjavani, Mahboobeh Kamali, Hamid Reza Baradaran

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)
6 Downloads (Pure)

Abstract

Background: Vitamin D deficiency is related to rickets in children, and it can increase the risk of osteoporosis in adulthood. The aim of our study was to estimate the prevalence of vitamin D deficiency among healthy Iranian children and adolescents. Vitamin D levels less than 20ng/ml and between 20 and 30ng/ml was considered as vitamin D deficiency and insufficiency, respectively. Methods: Relevant observational studies evaluating the prevalence of vitamin D deficiency through 1 January 1990 to 28 Dec 2016, were searched in several electronic databases including Iran-Medex, Scientific Information Database (SID), Irandoc, PubMed and NLM Gateway (for MEDLINE), Web of Science, and Scopus with no restriction on language. Only full-text articles were used for data extraction and synthesis after considering the inclusion/exclusion criteria. Results: 11 studies included; the data of four studies of Iranian newborns were withdrawn because of their high heterogeneity. The prevalence of vitamin D deficiency in Iranian boys and girls were 35% (CI 95% 34-37) and 61% (CI 95% 60-63), respectively. The prevalence of vitamin D insufficiency in Iranian children and adolescents was 31% (CI 95% 30-31). Conclusion: It seems that the prevalence of vitamin D deficiency is very high among Iranian children and adolescents. The present findings could provide practical information for healthcare decision makers.

Original languageEnglish
Article number83
JournalMedical Journal of the Islamic Republic of Iran
Volume32
Issue number1
DOIs
Publication statusPublished - 8 Sep 2018

Keywords

  • vitamin D deficiency
  • insufficiency
  • prevalence
  • children
  • Iran

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