Prevención de enfermedades mitocondriales

una esperanza a través del uso de técnicas de reproducción asistida

Translated title of the contribution: Prevention of mitochondrial diseases: a hope through assisted reproductive technologies

Research output: Contribution to journalArticle

Abstract

Mitochondrial diseases are a heterogenic and poorly studied group of diseases, considered serious in most cases and currently without treatment. Although assisted reproduction proposed strategies to prevent them, such as pre-implantation genetic diagnosis, these techniques are not sufficiently successful. However, the recent publication of two assistedreproduction techniques – meiotic spindle transfer in nonhuman primates and pronuclear transfer in humans – generate a clear ray of hope for the prevention of these diseases. This review analyzes the characteristics and meaning of these new findings and their future clinical implications.

Original languageSpanish
Pages (from-to)172-5
Number of pages4
JournalGaceta Medica de Mexico
Volume147
Issue number2
Publication statusPublished - 30 Apr 2011

Fingerprint

Mitochondrial Diseases
Assisted Reproductive Techniques
Genetic Techniques
Spindle Apparatus
Primates
Reproduction
Therapeutics
Mitochondrial Replacement Therapy

Keywords

  • Humans
  • Mitochondrial Diseases
  • Nuclear Transfer Techniques
  • Reproductive Techniques, Assisted
  • English Abstract
  • Journal Article
  • Review

Cite this

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title = "Prevenci{\'o}n de enfermedades mitocondriales: una esperanza a trav{\'e}s del uso de t{\'e}cnicas de reproducci{\'o}n asistida",
abstract = "Mitochondrial diseases are a heterogenic and poorly studied group of diseases, considered serious in most cases and currently without treatment. Although assisted reproduction proposed strategies to prevent them, such as pre-implantation genetic diagnosis, these techniques are not sufficiently successful. However, the recent publication of two assistedreproduction techniques – meiotic spindle transfer in nonhuman primates and pronuclear transfer in humans – generate a clear ray of hope for the prevention of these diseases. This review analyzes the characteristics and meaning of these new findings and their future clinical implications.",
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author = "{Pina Aguilar}, {Raul Eduardo}",
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journal = "Gaceta Medica de Mexico",
issn = "0016-3813",
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AU - Pina Aguilar, Raul Eduardo

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N2 - Mitochondrial diseases are a heterogenic and poorly studied group of diseases, considered serious in most cases and currently without treatment. Although assisted reproduction proposed strategies to prevent them, such as pre-implantation genetic diagnosis, these techniques are not sufficiently successful. However, the recent publication of two assistedreproduction techniques – meiotic spindle transfer in nonhuman primates and pronuclear transfer in humans – generate a clear ray of hope for the prevention of these diseases. This review analyzes the characteristics and meaning of these new findings and their future clinical implications.

AB - Mitochondrial diseases are a heterogenic and poorly studied group of diseases, considered serious in most cases and currently without treatment. Although assisted reproduction proposed strategies to prevent them, such as pre-implantation genetic diagnosis, these techniques are not sufficiently successful. However, the recent publication of two assistedreproduction techniques – meiotic spindle transfer in nonhuman primates and pronuclear transfer in humans – generate a clear ray of hope for the prevention of these diseases. This review analyzes the characteristics and meaning of these new findings and their future clinical implications.

KW - Humans

KW - Mitochondrial Diseases

KW - Nuclear Transfer Techniques

KW - Reproductive Techniques, Assisted

KW - English Abstract

KW - Journal Article

KW - Review

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VL - 147

SP - 172

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JO - Gaceta Medica de Mexico

JF - Gaceta Medica de Mexico

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