Progression of varicose veins and chronic venous insufficiency in the general population in the Edinburgh Vein Study

Amanda J. Lee; Lindsay A. Robertson; Sheila M. Boghossian; Paul L. Allan; C. Vaughan Ruckley; F. Gerald R Fowkes; Christine J. Evans

doi:10.1016/j.jvsv.2014.09.008

Progression of varicose veins and chronic venous insufficiency in the general population in the Edinburgh Vein Study

Amanda J. Lee, Lindsay A. Robertson, Sheila M. Boghossian, Paul L. Allan, C. Vaughan Ruckley, F. Gerald R Fowkes^*, Christine J. Evans

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

78 Citations (Scopus)

Abstract

Objective: The natural history in the general population of chronic venous disease in the legs is not well understood. This has limited our ability to predict which patients will deteriorate and to assign clinical priorities. The aims of this study were to describe the progression of trunk varicose veins and chronic venous insufficiency (CVI) in the general population, to identify important lifestyle and clinical prognostic factors, and to determine the relationship between venous reflux and progression.

Methods:The Edinburgh Vein Study is a population-based cohort study in which randomly selected adults aged 18 to 64 years had an examination at baseline. This included a questionnaire on lifestyle and clinical factors, standardized assessment and classification of venous disease in the legs, and duplex scan to detect venous reflux in eight segments of each leg. A follow-up examination 13 years later included a reclassification of venous disease to ascertain progression in the development or increase in severity of varicose veins and CVI

Original language	English
Pages (from-to)	18-26
Number of pages	9
Journal	Journal of Vascular Surgery: Venous and Lymphatic Disorders
Volume	3
Issue number	1
Early online date	1 Nov 2014
DOIs	https://doi.org/10.1016/j.jvsv.2014.09.008
Publication status	Published - 1 Jan 2015

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title = "Progression of varicose veins and chronic venous insufficiency in the general population in the Edinburgh Vein Study",

abstract = "Objective: The natural history in the general population of chronic venous disease in the legs is not well understood. This has limited our ability to predict which patients will deteriorate and to assign clinical priorities. The aims of this study were to describe the progression of trunk varicose veins and chronic venous insufficiency (CVI) in the general population, to identify important lifestyle and clinical prognostic factors, and to determine the relationship between venous reflux and progression.Methods:The Edinburgh Vein Study is a population-based cohort study in which randomly selected adults aged 18 to 64 years had an examination at baseline. This included a questionnaire on lifestyle and clinical factors, standardized assessment and classification of venous disease in the legs, and duplex scan to detect venous reflux in eight segments of each leg. A follow-up examination 13 years later included a reclassification of venous disease to ascertain progression in the development or increase in severity of varicose veins and CVI",

author = "Lee, {Amanda J.} and Robertson, {Lindsay A.} and Boghossian, {Sheila M.} and Allan, {Paul L.} and Ruckley, {C. Vaughan} and Fowkes, {F. Gerald R} and Evans, {Christine J.}",

note = "Acknowledgements The authors thank Angie Balfour and Heather Spence at the Wellcome Trust Clinical Research Facility (Edinburgh) for data collection and Karen Gallagher and Maggie Glass at the Vascular Laboratory, Royal Infirmary of Edinburgh, for training in duplex ultrasound.",

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doi = "10.1016/j.jvsv.2014.09.008",

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T1 - Progression of varicose veins and chronic venous insufficiency in the general population in the Edinburgh Vein Study

AU - Lee, Amanda J.

AU - Robertson, Lindsay A.

AU - Boghossian, Sheila M.

AU - Allan, Paul L.

AU - Ruckley, C. Vaughan

AU - Fowkes, F. Gerald R

AU - Evans, Christine J.

N1 - Acknowledgements The authors thank Angie Balfour and Heather Spence at the Wellcome Trust Clinical Research Facility (Edinburgh) for data collection and Karen Gallagher and Maggie Glass at the Vascular Laboratory, Royal Infirmary of Edinburgh, for training in duplex ultrasound.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Objective: The natural history in the general population of chronic venous disease in the legs is not well understood. This has limited our ability to predict which patients will deteriorate and to assign clinical priorities. The aims of this study were to describe the progression of trunk varicose veins and chronic venous insufficiency (CVI) in the general population, to identify important lifestyle and clinical prognostic factors, and to determine the relationship between venous reflux and progression.Methods:The Edinburgh Vein Study is a population-based cohort study in which randomly selected adults aged 18 to 64 years had an examination at baseline. This included a questionnaire on lifestyle and clinical factors, standardized assessment and classification of venous disease in the legs, and duplex scan to detect venous reflux in eight segments of each leg. A follow-up examination 13 years later included a reclassification of venous disease to ascertain progression in the development or increase in severity of varicose veins and CVI

AB - Objective: The natural history in the general population of chronic venous disease in the legs is not well understood. This has limited our ability to predict which patients will deteriorate and to assign clinical priorities. The aims of this study were to describe the progression of trunk varicose veins and chronic venous insufficiency (CVI) in the general population, to identify important lifestyle and clinical prognostic factors, and to determine the relationship between venous reflux and progression.Methods:The Edinburgh Vein Study is a population-based cohort study in which randomly selected adults aged 18 to 64 years had an examination at baseline. This included a questionnaire on lifestyle and clinical factors, standardized assessment and classification of venous disease in the legs, and duplex scan to detect venous reflux in eight segments of each leg. A follow-up examination 13 years later included a reclassification of venous disease to ascertain progression in the development or increase in severity of varicose veins and CVI

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Progression of varicose veins and chronic venous insufficiency in the general population in the Edinburgh Vein Study

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