Properties of the copper(II)-histidine complex obtained after dialysis of human plasma with histidine

Tony Venelinov, Sonia Arpadjan, Irina Karadjova, John Hamilton Beattie

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    The copper(II)-histidine complex obtained following dialysis of human plasma with histidine was investigated using various types of extraction systems and ion exchange resins. According to the results obtained, the Cu(II)-histidine complex formed under the dialysis conditions has one positive charge. Preconcentration of copper from the dialysis solution was achieved by its extraction as a dithiocarbamate complex and by sorption on cation-exchange resin or onto chelate sorbent.
    Original languageEnglish
    Pages (from-to)105-112
    Number of pages8
    JournalActa Pharmaceutica
    Issue number1
    Publication statusPublished - 1 Mar 2006



    • Adsorption
    • Adult
    • Copper
    • Dialysis
    • Histidine
    • Humans
    • Male
    • Middle Aged

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