Escherichia coli are exposed to toxic electrophiles from both endogenous and exogenous sources. To survive, E. coli have developed novel protective mechanisms that appear unique to bacteria. In the absence of one of these mechanisms, electrophiles induce rapid killing. Hence it appears that electrophile-protective mechanisms represent novel targets for antibacterial drug research.
|Number of pages||6|
|Journal||Trends in Microbiology|
|Publication status||Published - 1999|
- METHYLGLYOXAL PRODUCTION
- POTASSIUM CHANNELS