Proteomic analysis of plasma, platelets and PBMC in nutritional intervention studies

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Abstract

    The use of proteomics as a valuable tool in nutrition research is discussed in this chapter. Proteome analysis of plasma and blood cells such as platelets and peripheral blood mononuclear cells (PBMC) can identify thousands of proteins that: potentially provide valuable new biomarkers for health; reveal early indications of disease risk; assist in establishing dietary responders from non-responders; and enable discovery of mechanisms of action for beneficial food components. The different proteomic techniques are also described with their corresponding advantages and disadvantages in nutrition research.
    Original languageEnglish
    Title of host publicationDesign of human nutrigenomic studies
    EditorsSiân Astley , Linda Penn
    Place of PublicationWageningen
    PublisherWageningen Academic Publishers
    Pages55-64
    Number of pages10
    ISBN (Print)978-90-8686-094-4 , 908686094X
    Publication statusPublished - 1 Jul 2009

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