The use of proteomics as a valuable tool in nutrition research is discussed in this chapter. Proteome analysis of plasma and blood cells such as platelets and peripheral blood mononuclear cells (PBMC) can identify thousands of proteins that: potentially provide valuable new biomarkers for health; reveal early indications of disease risk; assist in establishing dietary responders from non-responders; and enable discovery of mechanisms of action for beneficial food components. The different proteomic techniques are also described with their corresponding advantages and disadvantages in nutrition research.
|Title of host publication||Design of human nutrigenomic studies|
|Editors||Siân Astley , Linda Penn|
|Place of Publication||Wageningen|
|Publisher||Wageningen Academic Publishers|
|Number of pages||10|
|ISBN (Print)||978-90-8686-094-4 , 908686094X|
|Publication status||Published - 1 Jul 2009|
De Roos, B. (2009). Proteomic analysis of plasma, platelets and PBMC in nutritional intervention studies. In S. Astley , & L. Penn (Eds.), Design of human nutrigenomic studies (pp. 55-64). Wageningen Academic Publishers.