Psychosocial interventions for depression in dialysis patients

K S Rabindranath, Clare Louise Daly, J A Butler, P J Roderick, Sheila Ann Wallace, Alison MacLeod

Research output: Contribution to journalLiterature reviewpeer-review

29 Citations (Scopus)

Abstract

Background: Depression is the most common psychological problem in the dialysis population. The diagnosis of depression in dialysis patients is confounded by the fact that several symptoms of uraemia mimic the somatic components of depression. It affects the physical, psychological and social well being of the dialysis population in several ways.
Objectives: The aim of this systematic review was to assess the effectiveness of psychosocial interventions in the treatment of depression in patients who are dialysed for end-stage renal disease.
Search strategy A comprehensive search strategy was employed to identify all randomised controlled trials (RTs) relevant to the treatment of depression in dialysis patients. The following databases were searched MEDLINE (1966-October 2003), EMBASE (1980-October 2003), PsycINFO (1872-October 2003) and The Cochrane Library (issue 3, 2003). Authors of potential studies were contacted, reference lists of identified RCTs and relevant narrative reviews were screened.
Selection criteria RCTs comparing any psychosocial intervention with control intervention or no intervention in depressed dialysis patients.
Data collection and analysis Data were to be abstracted by two investigators independently on to a standard form and entered in to Review Manager 4.2. Relative risk (RR) for dichotomous data and a (weighted) mean difference (MD) for continuous data were to be calculated with 9% confidence intervals (CI).
Main results Despite extensive searching, no RCTs were identified.
Authors' conclusions Data were not available to draw conclusions a bout the effectiveness of psychosocial interventions in the treatment of depression in the chronic dialysis population, as we did not find any RCTs of psychosocial interventions to treat depression in dialysis patients. This review highlights the need for commencing and completing adequately powered RCTs to address the issue of psychosocial interventions for depression in dialysis patients.
SYNOPSIS Depression is the most common psychological problem in the chronic dialysis population and it affects their physical, mental and social well-being. The aim of this review was to determine the effectiveness of psychosocial interventions (e.g. cognitive behavioural therapy) for treating depressed dialysis patients. No relevant randomised controlled trials were identified. Large, long-term studies are needed in this area .

Original languageEnglish
Article numberCD004542
JournalCochrane Database of Systematic Reviews
Issue number3
DOIs
Publication statusPublished - 20 Jul 2005

Keywords

  • stage renal disese
  • quality of life
  • hemodialysis patients
  • behavioral compliance
  • kidney dialysis
  • mortality
  • exercise
  • illness
  • adjustment
  • survival

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