Putrescine bisamides from Aglaia gigantea

N.D. Tu, R. Edrada, R. Ebel, V. Wray, W. Frank, T.D. Anh, H.L. Wen, P. Proksch

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Phytochemical analysis of the leaves of Aglaia gigantea collected in Vietnam yielded three cinnamoyl putrescine bisamide derivatives, which included the known compound dasyclamide (1), as well as two new natural products, gigantamide A (2) and grandiamide D (3). In this study, the structure of dasyclamide (1) was confirmed by X-ray crystallography. The structures of the two new alkaloids, gigantamide A (2) and grandiamide D (3), were elucidated through extensive 1D and 2D NMR spectroscopy and analysis of their mass spectrometric (ESIMS, HRQTOFMS) data. The absolute configuration of grandiamide D (3) was determined via Mosher ester derivatization.
Original languageEnglish
Pages (from-to)1640-1643
Number of pages4
JournalJournal of Natural Products
Volume70
Issue number10
DOIs
Publication statusPublished - 1 Oct 2007

Fingerprint

Aglaia
Putrescine
Vietnam
X ray crystallography
X Ray Crystallography
Phytochemicals
Biological Products
Alkaloids
Nuclear magnetic resonance spectroscopy
Esters
Magnetic Resonance Spectroscopy
Derivatives
grandiamide D
dasyclamide
gigantamide A

Cite this

Tu, N. D., Edrada, R., Ebel, R., Wray, V., Frank, W., Anh, T. D., ... Proksch, P. (2007). Putrescine bisamides from Aglaia gigantea. Journal of Natural Products, 70(10), 1640-1643. https://doi.org/10.1021/np070184w

Putrescine bisamides from Aglaia gigantea. / Tu, N.D.; Edrada, R.; Ebel, R.; Wray, V.; Frank, W.; Anh, T.D.; Wen, H.L.; Proksch, P.

In: Journal of Natural Products, Vol. 70, No. 10, 01.10.2007, p. 1640-1643.

Research output: Contribution to journalArticle

Tu, ND, Edrada, R, Ebel, R, Wray, V, Frank, W, Anh, TD, Wen, HL & Proksch, P 2007, 'Putrescine bisamides from Aglaia gigantea', Journal of Natural Products, vol. 70, no. 10, pp. 1640-1643. https://doi.org/10.1021/np070184w
Tu ND, Edrada R, Ebel R, Wray V, Frank W, Anh TD et al. Putrescine bisamides from Aglaia gigantea. Journal of Natural Products. 2007 Oct 1;70(10):1640-1643. https://doi.org/10.1021/np070184w
Tu, N.D. ; Edrada, R. ; Ebel, R. ; Wray, V. ; Frank, W. ; Anh, T.D. ; Wen, H.L. ; Proksch, P. / Putrescine bisamides from Aglaia gigantea. In: Journal of Natural Products. 2007 ; Vol. 70, No. 10. pp. 1640-1643.
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