The article introduces an information-theoretic approach to detect and quantify causal couplings in the complex cardiovascular system. In a first step a causal algorithm detects the coupling delays and in a second step the causal strength of each coupling mechanism is quantified using the recently introduced momentary information transfer. As a preliminary example, the method is applied to time series of respiration, systolic and diastolic blood pressure, and heart rate of pregnant healthy women and women suffering from pre-eclampsia. A possible explanation for the influence of heart rate on systolic blood pressure is found.
Runge, J., Riedl, M., Stepan, H., Wessel, N., & Kurths, J. (2015). Quantifying the causal strength of multivariate cardiovascular couplings with momentary information transfer. Physiological Measurement, 36(4), 149-150. https://doi.org/10.1109/ESGCO.2014.6847563